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Additional Topics Details for this Page
Article Count
- 7
Cumulative Knowledge
- 7
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Quick Summary: Current access displays 2 out of 7 associated Problem Substances
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Cumulative Knowledge
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Focus Articles
Sodium Fluoride
2
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Quick Summary: Current access displays 2 out of 10 associated Diseases
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View the Evidence: Adverse Pharmacological Actions
"Effect of pesticides on cell survival in liver and brain rat tissues."
Click here to read the entire abstract
Pubmed Data
: Ecotoxicol Environ Saf. 2009 Oct ;72(7):2025-32. Epub 2009 Jun 2. PMID:
19493570
Article Published Date
: Oct 01, 2009
Study Type
: In Vitro Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage : CK(475) : AC(175)
,
Glyphosate Toxicity : CK(22) : AC(12)
,
Lipid Peroxidation : CK(403) : AC(127)
,
Neurotoxicity : CK(37) : AC(15)
,
Parkinson Disease : CK(543) : AC(79)
,
Pesticide Toxicity : CK(147) : AC(45)
Problem Substances
:
Dimethoate : CK(3) : AC(1)
,
Glyphosate : CK(365) : AC(116)
,
Pesticides : CK(699) : AC(70)
,
Zineb : CK(1) : AC(1)
Adverse Pharmacological Actions
:
Apoptotic : CK(8) : AC(7)
,
Hepatotoxic : CK(283) : AC(80)
,
Neurotoxic : CK(1076) : AC(179)
,
Oxidant : CK(104) : AC(37)
A commercial formulation of glyphosate inhibits proliferation and differentiation to adipocytes and induces programmed cell death in 3T3-L1 fibroblasts.
Click here to read the entire abstract
Pubmed Data
: Toxicol In Vitro. 2012 Apr 21. Epub 2012 Apr 21. PMID:
22546541
Article Published Date
: Apr 21, 2012
Study Type
: In Vitro Study
Additional Links
Diseases
:
Glyphosate Toxicity : CK(22) : AC(12)
Problem Substances
:
Glyphosate : CK(365) : AC(116)
Adverse Pharmacological Actions
:
Apoptotic : CK(8) : AC(7)
,
Cytotoxic : CK(73) : AC(35)
Bisphosphonates may induce gastrointestinal damage through the inhibition of the mevalonate pathway.
Click here to read the entire abstract
Pubmed Data
: Bone. 2001 Oct;29(4):336-43. PMID:
11595616
Article Published Date
: Oct 01, 2001
Study Type
: In Vitro Study
Additional Links
Diseases
:
Drug-Induced Toxicity: Gastrointestinal : CK(21) : AC(3)
,
Gastrointestinal Diseases : CK(38) : AC(14)
Additional Keywords
:
Mevalonate Pathway Inhibition : CK(1) : AC(1)
Problem Substances
:
Bisphosphonates : CK(496) : AC(61)
Adverse Pharmacological Actions
:
Apoptotic : CK(8) : AC(7)
Sodium fluoride exposure compromises hair follicle growth and accelerates programmed cell death.
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2010 Jan 5. Epub 2010 Jan 5. PMID:
20049553
Article Published Date
: Jan 05, 2010
Study Type
: In Vitro Study
Additional Links
Diseases
:
Hair Loss : CK(99) : AC(22)
,
Hair Quality Problems : CK(31) : AC(4)
Problem Substances
:
Sodium Fluoride : CK(88) : AC(26)
Adverse Pharmacological Actions
:
Apoptotic : CK(8) : AC(7)
,
Oxidant : CK(104) : AC(37)
Sodium fluoride may interfere with odontogenesis by inhibiting antioxidative enzymes and inducing programmed cell death.
Click here to read the entire abstract
Pubmed Data
: J Oral Pathol Med. 2010 Aug 3. Epub 2010 Aug 3. PMID:
20738751
Article Published Date
: Aug 03, 2010
Study Type
: In Vitro Study
Additional Links
Problem Substances
:
Sodium Fluoride : CK(88) : AC(26)
Adverse Pharmacological Actions
:
Apoptotic : CK(8) : AC(7)
,
Oxidant : CK(104) : AC(37)
Statin drugs decrease de novo cholesterol synthesis and increase apoptosis in rat and human periovulatory granulosa cells.
Click here to read the entire abstract
Pubmed Data
: Biol Reprod. 2005 Mar ;72(3):538-45. Epub 2004 Sep 22. PMID:
15385411
Article Published Date
: Mar 01, 2005
Study Type
: In Vitro Study
Additional Links
Diseases
:
Ovarian Diseases : CK(11) : AC(6)
,
Ovulation Disorders : CK(1) : AC(1)
,
Statin-Induced Pathologies : CK(1570) : AC(315)
Problem Substances
:
Lovastatin : CK(265) : AC(67)
,
Simvastatin : CK(713) : AC(143)
,
Statin Drugs : CK(3969) : AC(465)
Adverse Pharmacological Actions
:
Apoptotic : CK(8) : AC(7)
,
Endocrine Disruptor: Ovary : CK(2) : AC(2)
Statin drugs induce cell death in mouse kidney cells.
Click here to read the entire abstract
Pubmed Data
: Kidney Int. 1997 Oct ;52(4):962-72. PMID:
9328935
Article Published Date
: Oct 01, 1997
Study Type
: In Vitro Study
Additional Links
Diseases
:
Kidney Damage : CK(120) : AC(42)
,
Statin-Induced Pathologies : CK(1570) : AC(315)
Problem Substances
:
Statin Drugs : CK(3969) : AC(465)
Adverse Pharmacological Actions
:
Apoptotic : CK(8) : AC(7)
,
Cytotoxic : CK(73) : AC(35)
,
Nephrotoxic : CK(162) : AC(38)
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