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Additional Topics Details for this Page
Article Count
- 1
Cumulative Knowledge
- 18
Advanced Database Options
Limit Articles Displayed by the Following Study Types
Animal Study
Environmental
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What is Cumulative Knowledge?
Cumulative Knowledge
is determined by ascribing a numerical value to the various study types weighted in descending order as follows: (1) Meta-Analysis; (2) Human Study; (3) Human: Case Study; (4) Animal: Transgenic; (5) Animal; (6) In Vitro; (7) Review; and (8) Commentary.
Click here for a more thorough explanation.
Quick Summary: 2 associated Problem Substances
Name
Cumulative Knowledge
Article Count
Focus Articles
Glyphosate
2
1
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Roundup (herbicide)
2
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View the Evidence: Adverse Pharmacological Actions
4-Nonyphenol exposure may result in decreased population and ultimate disappearance of a catfish species.
Click here to read the entire abstract
Pubmed Data
: Arch Environ Contam Toxicol. 2012 Dec 11. Epub 2012 Dec 11. PMID:
23229197
Article Published Date
: Dec 10, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Chemical Poisoning: Accumulated Environmental Toxins : CK(17) : AC(4)
Problem Substances
:
Nonylphenol : CK(1) : AC(1)
Adverse Pharmacological Actions
:
Aquacidal : CK(2) : AC(1)
Both the general health condition and reproductive success of J. multidenatata (fish) could be seriously affected by Roundup.
Click here to read the entire abstract
Pubmed Data
: Arch Environ Contam Toxicol. 2012 Jan ;62(1):107-17. Epub 2011 Jun 4. PMID:
21643816
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Problem Substances
:
Glyphosate formulations : CK(386) : AC(121)
,
Roundup (herbicide) : CK(365) : AC(116)
Adverse Pharmacological Actions
:
Aquacidal : CK(2) : AC(1)
,
Endocrine Disruptor : CK(478) : AC(81)
,
Genotoxic : CK(146) : AC(61)
Components of the original formulation of Roundup exhibit significant toxicity in five North American anurans (frogs; keystone species).
Click here to read the entire abstract
Pubmed Data
: Ecotoxicol Environ Saf. 2012 Apr ;78:128-33. Epub 2011 Dec 3. PMID:
22137360
Article Published Date
: Mar 31, 2012
Study Type
: Animal Study
Additional Links
Problem Substances
:
Glyphosate : CK(368) : AC(118)
Adverse Pharmacological Actions
:
Aquacidal : CK(2) : AC(1)
,
Genotoxic : CK(146) : AC(61)
Environmentally relevant concentrations of Roundup can pose a health risk for fish populations.
Click here to read the entire abstract
Pubmed Data
: Mutagenesis. 2010 Sep ;25(5):523-30. Epub 2010 Jul 19. PMID:
20643706
Article Published Date
: Aug 31, 2010
Study Type
: Animal Study
Additional Links
Diseases
:
DNA damage : CK(711) : AC(293)
,
Lipid Peroxidation : CK(403) : AC(127)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
Problem Substances
:
Glyphosate : CK(368) : AC(118)
Adverse Pharmacological Actions
:
Aquacidal : CK(2) : AC(1)
,
Genotoxic : CK(146) : AC(61)
Fish exposed to a glyphosate-based herbicide undergo DNA damage.
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 2012 Mar 18 ;743(1-2):1-9. Epub 2012 Jan 14. PMID:
22266476
Article Published Date
: Mar 17, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
DNA damage : CK(711) : AC(293)
,
Oxidative Stress : CK(1945) : AC(710)
Pharmacological Actions
:
Antioxidants : CK(3653) : AC(1318)
Problem Substances
:
Glyphosate : CK(368) : AC(118)
Adverse Pharmacological Actions
:
Aquacidal : CK(2) : AC(1)
,
Genotoxic : CK(146) : AC(61)
Genotoxic effects of the herbicide Roundup(®) have been observed in the fish species Corydoras paleatus after short-term, environmentally low concentration exposure.
Click here to read the entire abstract
Pubmed Data
: Environ Monit Assess. 2012 Jul 22. Epub 2012 Jul 22. PMID:
22821326
Article Published Date
: Jul 21, 2012
Study Type
: Animal Study, Environmental
Additional Links
Diseases
:
Glyphosate Toxicity : CK(22) : AC(12)
Problem Substances
:
Glyphosate : CK(368) : AC(118)
,
Glyphosate formulations : CK(386) : AC(121)
,
Roundup (herbicide) : CK(365) : AC(116)
Adverse Pharmacological Actions
:
Aquacidal : CK(2) : AC(1)
,
Genotoxic : CK(146) : AC(61)
Glyphosate exposure of the fish (Cnesterodon decemmaculatus) to environmentally relevant concentrations of glyphosate may cause neurotoxicity.
Click here to read the entire abstract
Pubmed Data
: Bull Environ Contam Toxicol. 2012 Jan ;88(1):6-9. PMID:
22002176
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Problem Substances
:
Glyphosate : CK(368) : AC(118)
Adverse Pharmacological Actions
:
Acetylcholinesterase inhibitor (xenobiotic) : CK(6) : AC(1)
,
Aquacidal : CK(2) : AC(1)
,
Neurotoxic : CK(1076) : AC(179)
Roundup causes oxidative stress in liver and inhibits acetylcholinesterase in muscle and brain of a neotropical fish.
Click here to read the entire abstract
Pubmed Data
: Chemosphere. 2010 Jan;78(3):294-9. Epub 2009 Nov 11. PMID:
19910015
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Additional Keywords
:
Environmental Pollutant : CK(32) : AC(15)
Problem Substances
:
Glyphosate : CK(368) : AC(118)
,
Roundup (herbicide) : CK(365) : AC(116)
Adverse Pharmacological Actions
:
Aquacidal : CK(2) : AC(1)
,
Hepatotoxic : CK(283) : AC(80)
,
Neurotoxic : CK(1076) : AC(179)
,
Oxidant : CK(104) : AC(37)
Roundup(®) formulation exhibits genotoxicity in blood cells of fish (Anguilla anguilla).
Click here to read the entire abstract
Pubmed Data
: Ecotoxicology. 2012 Jul ;21(5):1381-90. Epub 2012 Apr 8. PMID:
22526921
Article Published Date
: Jun 30, 2012
Study Type
: Animal Study
Additional Links
Problem Substances
:
Glyphosate : CK(368) : AC(118)
Adverse Pharmacological Actions
:
Aquacidal : CK(2) : AC(1)
,
Genotoxic : CK(146) : AC(61)
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