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Article Count - 23
Cumulative Knowledge - 107

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Quick Summary: Current access displays 2 out of 28 associated Problem Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Sunscreen	31	4	Log in \| Sign up
Organochlorine pesticides	30	3	Log in \| Sign up

Quick Summary: Current access displays 2 out of 13 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Breastfeeding Concerns: Chemical Exposure	25	5	Log in \| Sign up
Chemical Exposure	20	2	Log in \| Sign up

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View the Evidence: Adverse Pharmacological Actions

Based on oxybenzone and oxybenzone metabolites recovered in urine, between 1 and 2% of an applied sunscreen was absorbed over a 10-hour period.

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Pubmed Data : Lancet. 1997 Sep 20;350(9081):863-4. PMID: 9310609

Article Published Date : Sep 20, 1997

Study Type : Human Study

Additional Links

Problem Substances : Octyl salicylate : CK(22) : AC(4), Oxybenzone : CK(30) : AC(10), Sunscreen : CK(71) : AC(14)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Concentrations of persistent organic chemicals do not consistently decline during lactation and can increase for some women.

Click here to read the entire abstract

Pubmed Data : Environ Health Perspect. 2009 Oct;117(10):1625-31. Epub 2009 Jun 15. PMID: 20019916

Article Published Date : Oct 01, 2009

Study Type : Human Study

Additional Links

Diseases : Breastfeeding Concerns: Chemical Exposure : CK(91) : AC(15), Infant Chemical Exposures : CK(162) : AC(22)

Problem Substances : Dioxins : CK(28) : AC(9), Organochlorine pesticides : CK(260) : AC(30), Persistent organic pollutants (POPs) : CK(93) : AC(12), Polybrominated diphenylethers (PBDEs) : CK(26) : AC(5), Polychlorinated biphenyls (PCBs) : CK(179) : AC(24)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Maternal adipose tissue releases organochlorine pesticides into blood serum and they are carried over to umbilical cord blood.

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Pubmed Data : Bull Environ Contam Toxicol. 2011 Mar ;86(3):289-93. Epub 2011 Feb 3. PMID: 21290101

Article Published Date : Mar 01, 2011

Study Type : Human Study

Additional Links

Diseases : Pesticide Toxicity : CK(147) : AC(45), Prenatal Chemical Exposures : CK(322) : AC(86), Prenatal Nutrition: Prevention of Problems : CK(357) : AC(41)

Additional Keywords : Chemical: Lindane : CK(22) : AC(7)

Problem Substances : Organochlorine pesticides : CK(260) : AC(30), Pesticides : CK(699) : AC(70)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Perchlorate exposure is ubiquitous in the US and has been found to be widespread in food and drinking water.

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Pubmed Data : PLoS One. 2011;6(3):e17015. Epub 2011 Mar 4. PMID: 21394205

Article Published Date : Jan 01, 2011

Study Type : Human Study

Additional Links

Diseases : Perchlorate Toxicity : CK(116) : AC(8)

Problem Substances : Perchlorate : CK(100) : AC(28)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Persistent organochlorine pesticides are commonly found in breast milk samples from women in mainland China.

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Pubmed Data : Environ Pollut. 2011 Feb;159(2):524-31. Epub 2010 Nov 19. PMID: 21093969

Article Published Date : Feb 01, 2011

Study Type : Human Study

Additional Links

Diseases : Breastfeeding Concerns: Chemical Exposure : CK(91) : AC(15)

Additional Keywords : Meat-Pesticide Accumulation : CK(10) : AC(1)

Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) : CK(70) : AC(7), Organochlorine pesticides : CK(260) : AC(30), Pesticides : CK(699) : AC(70)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Sunscreen agents are absorbed through the skin and make it into systemic circulation throughout the body as measured by their presence in biological fluids.

Click here to read the entire abstract

Pubmed Data : J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Apr 25;803(2):225-31. PMID: 15063329

Article Published Date : Apr 25, 2004

Study Type : Human Study

Additional Links

Problem Substances : Homosalate : CK(11) : AC(2), Octyl salicylate : CK(22) : AC(4), Oxybenzone : CK(30) : AC(10)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Topical microfine titanium dioxide from sunscreens is capable of accumulating in the epidermis and dermis of humans subjects.

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Pubmed Data : Australas J Dermatol. 1996 Nov;37(4):185-7. PMID: 8961584

Article Published Date : Nov 01, 1996

Study Type : Human Study

Additional Links

Diseases : Chemical Exposure : CK(49) : AC(15)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Sunscreen : CK(71) : AC(14), Titanium Dioxide : CK(41) : AC(17)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Topically applied nanoparticle zinc oxide from sunscreen are capable of being absorbed through the human skin.

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Pubmed Data : Toxicol Sci. 2010 Nov;118(1):140-9. Epub 2010 Aug 12. PMID: 20705894

Article Published Date : Nov 01, 2010

Study Type : Human Study

Additional Links

Diseases : Chemical Exposure : CK(49) : AC(15)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Sunscreen : CK(71) : AC(14), Zinc Oxide : CK(18) : AC(8)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Bisphenol S (BPS) is more heat-stable and photo-resistant than bisphenol A (BPA).

Click here to read the entire abstract

Pubmed Data : Environ Toxicol Pharmacol. 2005 Jan ;19(1):121-30. PMID: 21783468

Article Published Date : Jan 01, 2005

Study Type : Environmental

Additional Links

Problem Substances : Bisphenol S : CK(21) : AC(9)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

BPS is not amenable to biodegradation and might be persistent and become an ecological burden.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Environ Res Public Health. 2009 Apr ;6(4):1472-84. Epub 2009 Apr 17. PMID: 19440529

Article Published Date : Apr 01, 2009

Study Type : Environmental

Additional Links

Diseases : Bisphenol S Toxicity : CK(16) : AC(1)

Problem Substances : Bisphenol S : CK(21) : AC(9)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Endocrine and toxic effects of Roundup, not just glyphosate, can be observed in mammals, and Roundup adjuvants enhance glyphosate bioavailability and/or bioaccumulation.

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Pubmed Data : Environ Health Perspect. 2005 Jun;113(6):716-20. PMID: 15929894

Article Published Date : Jun 01, 2005

Study Type : Animal Study

Additional Links

Additional Keywords : Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

Problem Substances : Glyphosate : CK(365) : AC(116)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23), Cytotoxic : CK(73) : AC(35), Endocrine Disruptor : CK(478) : AC(81)

Gestational and lactational transfer of melamine has been confirmed in an animal model.

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Pubmed Data : Food Chem Toxicol. 2011 Mar 30. Epub 2011 Mar 30. PMID: 21457748

Article Published Date : Mar 30, 2011

Study Type : Animal Study

Additional Links

Diseases : Breastfeeding Concerns: Chemical Exposure : CK(91) : AC(15), Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Melamine : CK(6) : AC(3)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Global weapons testing has resulted in radionuclide accumulation in crabs from Japan.

Click here to read the entire abstract

Pubmed Data : Mar Pollut Bull. 2010 Dec;60(12):2311-22. Epub 2010 Oct 14. PMID: 20950831

Article Published Date : Dec 01, 2010

Study Type : Animal Study

Additional Links

Diseases : Radiation-Induced Illness: Cesium-137 Exposure : CK(96) : AC(25), Radiation-Induced Illness: Plutonium : CK(15) : AC(8), Radiation-Induced Illness: Strontium 90 : CK(24) : AC(4)

Additional Keywords : Radioisotope In Food : CK(3) : AC(2)

Problem Substances : Cesium-137 : CK(37) : AC(7), Plutonium-239 : CK(6) : AC(4), Plutonium-240 : CK(6) : AC(4), Radionuclides : CK(54) : AC(14), Silver-108m : CK(2) : AC(1), Strontium-90 : CK(24) : AC(5)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Oxybenzone and DEET enhance the skin permeation of each other and accumulate in blood, liver and brain after repeated topical application.

Click here to read the entire abstract

Pubmed Data : Int J Toxicol. 2010 Oct 19. Epub 2010 Oct 19. PMID: 20959613

Article Published Date : Oct 19, 2010

Study Type : Animal Study

Additional Links

Problem Substances : Oxybenzone : CK(30) : AC(10)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Perchlorate in the feed-dairy continuum of the southwestern United States.

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2008 Jul 9;56(13):5443-50. Epub 2008 Jun 13. PMID: 18553887

Article Published Date : Jul 09, 2008

Study Type : Animal Study

Additional Links

Problem Substances : Perchlorate : CK(100) : AC(28)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

The glyphosate-based formula Roundup sigificantly increases the bioaccumulation of mercury in water fleas.

Click here to read the entire abstract

Pubmed Data : Environ Pollut. 2005 Nov;138(1):59-68. PMID: 15878796

Article Published Date : Nov 01, 2005

Study Type : Animal Study

Additional Links

Diseases : Mercury Poisoning : CK(162) : AC(44)

Problem Substances : Glyphosate : CK(365) : AC(116), Roundup (herbicide) : CK(365) : AC(116)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Toxicity and tissue accumulation of nonylphenol in Carassius auratus red variety, Grass carp and Sliver carp

Click here to read the entire abstract

Pubmed Data : Wei Sheng Yan Jiu. 2012 Sep ;41(5):785-9. PMID: 23213694

Article Published Date : Aug 31, 2012

Study Type : Animal Study

Additional Links

Problem Substances : Nonylphenol : CK(1) : AC(1)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

"Analysis of Bisphenol A, Nonylphenol and Natural Estrogens in Vegetables and Fruits Using Gas Chromatography-Tandem Mass Spectrometry."

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2012 Dec 6. Epub 2012 Dec 6. PMID: 23215552

Article Published Date : Dec 05, 2012

Study Type : Plant Study

Additional Links

Problem Substances : 17beta-estradiol : CK(38) : AC(7), Bisphenol A : CK(217) : AC(54)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

A model has been developed which predicts that the concentration of persistent organic pollutants in the infant body increase the first half year to about factor 3 above mother and decline thereafter to lower levels.

Click here to read the entire abstract

Pubmed Data : Environ Pollut. 2008 Nov;156(1):90-8. Epub 2008 Feb 14. PMID: 18280018

Article Published Date : Nov 01, 2008

Study Type : Commentary

Additional Links

Diseases : Breastfeeding Concerns: Chemical Exposure : CK(91) : AC(15)

Problem Substances : Persistent organic pollutants (POPs) : CK(93) : AC(12)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Denatured alcohol may increase the penetration of other chemicals through the skin and may itself exhibit inherent toxicity.

Click here to read the entire abstract

Pubmed Data : Int J Toxicol. 2008;27 Suppl 1:1-43. PMID: 18569160

Article Published Date : Jan 01, 2008

Study Type : Review

Additional Links

Problem Substances : Denatured Alcohol : CK(1) : AC(1), Sunscreen : CK(71) : AC(14)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Glyphosphate increases the bioaccumulation of depleted uranium in plants 17 fold.

Click here to read the entire abstract

Pubmed Data : Int J Phytoremediation. 2010 Aug;12(6):550-61. PMID: 21166280

Article Published Date : Aug 01, 2010

Study Type : In Vitro Study

Additional Links

Diseases : Uranium Poisoning : CK(28) : AC(19)

Additional Keywords : Problem Substance Synergy : CK(5) : AC(3)

Problem Substances : Glyphosate : CK(365) : AC(116), Uranium : CK(46) : AC(21)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Octyl salicylate is capable of penetrating the skin and being absorbed by the body.

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 1997 Dec;35(12):1219-25. PMID: 9449227

Article Published Date : Dec 01, 1997

Study Type : In Vitro Study

Additional Links

Problem Substances : Octyl salicylate : CK(22) : AC(4)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Perchlorate accumulates in forage and edible vegetation.

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2005 Jan 26;53(2):369-73. PMID: 15656674

Article Published Date : Jan 26, 2005

Study Type : In Vitro Study

Additional Links

Problem Substances : Perchlorate : CK(100) : AC(28)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Perchlorate is not metabolized or re-translocated within lettuce leaves, indicating it is a persistent environmental pollutant.

Click here to read the entire abstract

Pubmed Data : Environ Sci Technol. 2008 Dec 15;42(24):9437-42. PMID: 19174928

Article Published Date : Dec 15, 2008

Study Type : In Vitro Study

Additional Links

Problem Substances : Perchlorate : CK(100) : AC(28)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Plants are bio-monitors and bio-accumulators of radionuclides, as evidenced by the Savannah River Site.

Click here to read the entire abstract

Pubmed Data : J Environ Monit. 2011 Mar 16. Epub 2011 Mar 16. PMID: 21412545

Article Published Date : Mar 16, 2011

Study Type : Review

Additional Links

Diseases : Radionuclides: Bioremediation Research : CK(6) : AC(6)

Problem Substances : Cesium-137 : CK(37) : AC(7), Plutonium 238 : CK(5) : AC(4), Plutonium-239 : CK(6) : AC(4), Plutonium-240 : CK(6) : AC(4), Potassium-40 : CK(1) : AC(1), Radionuclides : CK(54) : AC(14)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

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