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Cell Cycle Inhibitor

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Article Count - 1
Cumulative Knowledge - 3

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Cumulative Knowledge is determined by ascribing a numerical value to the various study types weighted in descending order as follows: (1) Meta-Analysis; (2) Human Study; (3) Human: Case Study; (4) Animal: Transgenic; (5) Animal; (6) In Vitro; (7) Review; and (8) Commentary.

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Quick Summary: 1 associated Problem Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Glyphosate	1	1	Log in \| Sign up

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View the Evidence: Adverse Pharmacological Actions

"Formulated glyphosate activates the DNA-response checkpoint of the cell cycle leading to the prevention of G2/M transition."

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Pubmed Data : Toxicol Sci. 2004 Dec ;82(2):436-42. Epub 2004 Sep 16. PMID: 15375296

Article Published Date : Dec 01, 2004

Study Type : In Vitro Study

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Problem Substances : Glyphosate : CK(365) : AC(116)

Adverse Pharmacological Actions : Cell Cycle Inhibitor : CK(3) : AC(1), Cytotoxic : CK(73) : AC(35)

A glyphosate-based pesticide impinges on transcription.

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Pubmed Data : Toxicol Appl Pharmacol. 2005 Feb 15 ;203(1):1-8. PMID: 15694458

Article Published Date : Feb 15, 2005

Study Type : In Vitro Study

Additional Links

Problem Substances : Glyphosate : CK(365) : AC(116), Polyoxyethylene amine : CK(12) : AC(7)

Adverse Pharmacological Actions : Cell Cycle Inhibitor : CK(3) : AC(1), Cytotoxic : CK(73) : AC(35)

Glyphosate-based pesticides adversely affect cell cycle regulation at concentrations 500 to 4000 times lower than used in agriculatural applications.

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Pubmed Data : Biol Cell. 2004 Apr ;96(3):245-9. PMID: 15182708

Article Published Date : Apr 01, 2004

Study Type : In Vitro Study

Additional Links

Diseases : DNA damage : CK(711) : AC(293)

Problem Substances : Glyphosate : CK(365) : AC(116)

Adverse Pharmacological Actions : Cell Cycle Inhibitor : CK(3) : AC(1), Cytotoxic : CK(73) : AC(35), Genotoxic : CK(146) : AC(61)

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