Download Now

Your Token Count

0

Sign in to Purchase/Download Documents

Sign in / Register

User login

Social Networking

Support Free Media

Cytotoxic

User Options

A Membership is required. Please Login or Create an account to get started

Request us to build a Downloadable Document Product on this Topic

Make a Request for GMI to add more Articles on this Topic Immediately (Purchase Required)

View a Printer Friendly version of this page

E-mail this page to a friend

Perform a Search with this Topic

Hover over an icon for more information

Additional Topics Details for this Page

Article Count - 35
Cumulative Knowledge - 76

Advanced Database Options

Limit Articles Displayed by the Following Study Types

Available Sorting Options

Limited to Members Only

By default, all articles on GreenMedInfo.com are sorted based on the content type which best reflects the data which most users are searching for. For instance, people viewing substances are generally most interested in viewing diseases that these substances have shown to have positive influences. This section is for allowing more advanced sorting methods. Currently, these advanced sorting methods are available for members only. If you are already a member, you can sign in by clicking here. If you do not currently have a user account, and would like to create one/become a member, click here to begin the singup process.

Currently Available Sorting Options

Article Published Date - Sort all displayed articles by their published date
Quick Summary Fieldsets - Sort alphabetically, rather than by Cumulative Knowledge
Cumulative Knowledge - Default sorting method. Allows you to sort descendingly

What is Cumulative Knowledge?

Cumulative Knowledge is determined by ascribing a numerical value to the various study types weighted in descending order as follows: (1) Meta-Analysis; (2) Human Study; (3) Human: Case Study; (4) Animal: Transgenic; (5) Animal; (6) In Vitro; (7) Review; and (8) Commentary.

Click here for a more thorough explanation.

Quick Summary: Current access displays 2 out of 35 associated Problem Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Statin Drugs	15	6	Log in \| Sign up
Lovastatin	14	5	Log in \| Sign up

Quick Summary: Current access displays 2 out of 21 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Cornea Damage	10	1	Log in \| Sign up
Drug-Induced Toxicity	10	1	Log in \| Sign up

Currently Viewing Free Sample of Member Only Features

Although all 19,000+ articles on GreenMedInfo.com are made entirely free to view as an educational service to the public, we provide a powerful set of enhanced data comprehension and retrieval tools for subscribing members. Above you are viewing a free preview, limited to 2 rows, of the membership feature called "Cumulative Knowledge" (learn more).

The Focus Article Feature is not enabled.

Upgrading to the Member role gives you access to unlimited rows of Cumulative Knowledge data.

To Participate

Click here to login
Click here to create an account

View the Evidence: Adverse Pharmacological Actions

Pepper spray may result in damage to corneal nerve terminals with physical symptoms that last at least a week.

Click here to read the entire abstract

Pubmed Data : Invest Ophthalmol Vis Sci. 2000 Jul ;41(8):2138-47. PMID: 10892855

Article Published Date : Jul 01, 2000

Study Type : Human Study

Additional Links

Diseases : Cornea Damage : CK(60) : AC(5)

Pharmacological Actions : Neuritogenic : CK(98) : AC(48)

Additional Keywords : Plant Extracts : CK(3572) : AC(1216)

Anti Therapeutic Actions : Pepper Spraying : CK(85) : AC(11)

Problem Substances : Pepper Spray : CK(85) : AC(11)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35), Neurotoxic : CK(1076) : AC(179)

Statin drugs reduce coq10 levels which may result in mitochondrial dysfunction and cellular damage.

Click here to read the entire abstract

Pubmed Data : J Clin Pharmacol. 1993 Mar;33(3):226-9. PMID: 8463436

Article Published Date : Mar 01, 1993

Study Type : Human Study

Additional Links

Diseases : Drug-Induced Toxicity : CK(560) : AC(78), High Cholesterol : CK(1718) : AC(198), Myopathies : CK(252) : AC(51)

Additional Keywords : Drug-Nutrient Depletion : CK(64) : AC(7), Statin-Coq10 Depletion : CK(36) : AC(5)

Problem Substances : Lovastatin : CK(265) : AC(67), Pravastatin : CK(239) : AC(40), Simvastatin : CK(713) : AC(143), Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35)

Glyphosate adjuvants are not inactive, and exert cytotoxic effects at concentrations as low as 1 ppm.

Click here to read the entire abstract

Pubmed Data : Toxicology. 2012 Sep 21. Epub 2012 Sep 21. PMID: 23000283

Article Published Date : Sep 20, 2012

Study Type : Human In Vitro

Additional Links

Problem Substances : Ethoxylated adjuvants : CK(5) : AC(1), Glyphosate : CK(365) : AC(116), Glyphosate formulations : CK(356) : AC(107)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35)

A two-generational reproductive study of zinc chloride in rats demonstrates it causes significant pathological changes in a wide range of tissues.

Click here to read the entire abstract

Pubmed Data : J Environ Sci Health B. 2007 May;42(4):403-15. PMID: 17474020

Article Published Date : May 01, 2007

Study Type : Animal Study

Additional Links

Problem Substances : Zinc Chloride : CK(21) : AC(8)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35), Genotoxic : CK(146) : AC(61), Teratogenic : CK(304) : AC(59)

Cupric sulfate and cadmium have genotoxic and cytotoxic effects.

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2005 Apr;43(4):569-74. PMID: 15721204

Article Published Date : Apr 01, 2005

Study Type : Animal Study

Additional Links

Problem Substances : Cadmium : CK(14) : AC(4), Cupric Sulfate : CK(54) : AC(19)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35), Genotoxic : CK(146) : AC(61)

Endocrine and toxic effects of Roundup, not just glyphosate, can be observed in mammals, and Roundup adjuvants enhance glyphosate bioavailability and/or bioaccumulation.

Click here to read the entire abstract

Pubmed Data : Environ Health Perspect. 2005 Jun;113(6):716-20. PMID: 15929894

Article Published Date : Jun 01, 2005

Study Type : Animal Study

Additional Links

Additional Keywords : Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

Problem Substances : Glyphosate : CK(365) : AC(116)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23), Cytotoxic : CK(73) : AC(35), Endocrine Disruptor : CK(478) : AC(81)

Oral administration of titanium dioxide nanoparticles cause liver and heart injury, and wide distribution in the liver, spleen, kidneys and lung tissue.

Click here to read the entire abstract

Pubmed Data : Toxicol Lett. 2007 Jan 30;168(2):176-85. Epub 2006 Dec 9. PMID: 17197136

Article Published Date : Jan 30, 2007

Study Type : Animal Study

Additional Links

Diseases : Cardiovascular Diseases : CK(5138) : AC(641), Chemical Exposure : CK(49) : AC(15), Liver Damage : CK(597) : AC(213)

Problem Substances : Titanium Dioxide : CK(41) : AC(17)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35)

Six food coloring agents have cytotoxic effects and amplify the toxicity of a chemical in a rat model of liver impairment.

Click here to read the entire abstract

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2000 Jun;46(3):130-6. PMID: 10955279

Article Published Date : Jun 01, 2000

Study Type : Animal Study

Additional Links

Diseases : Chemically-Induced Liver Damage : CK(475) : AC(175)

Additional Keywords : Drug-Plant-Vitamin Synergies : CK(1011) : AC(268)

Problem Substances : Brilliant Blue FCF : CK(4) : AC(3), Erythrosine : CK(2) : AC(1), FD&C Red #40 : CK(4) : AC(2), Food Colorings : CK(132) : AC(23), Ponceau 4R (New Coccine) : CK(2) : AC(1), Tartrazine (Yellow Food Dye) : CK(22) : AC(8)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35), Hepatotoxic : CK(283) : AC(80)

Study: Oral and intracheal toxicities of Roundup and its components.

Click here to read the entire abstract

Pubmed Data : Vet Hum Toxicol. 1997 Jun;39(3):147-51. PMID: 9167243

Article Published Date : Jun 01, 1997

Study Type : Animal Study

Additional Links

Problem Substances : Glyphosate : CK(365) : AC(116), Polyoxyethylene amine : CK(12) : AC(7), Roundup (herbicide) : CK(346) : AC(107)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35)

Titanium dioxide nanoparticles cause acute toxicity, thrombosis, liver, lung and kidney damage when injected into mice.

Click here to read the entire abstract

Pubmed Data : J Appl Toxicol. 2009 May;29(4):330-7. PMID: 19156710

Article Published Date : May 01, 2009

Study Type : Animal Study

Additional Links

Diseases : Kidney Damage : CK(120) : AC(42), Lung Damage : CK(8) : AC(4)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Titanium Dioxide : CK(41) : AC(17)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35)

Triclosan bioconcentrates and exhibits toxicity to amphibian larvae.

Click here to read the entire abstract

Pubmed Data : Comp Biochem Physiol C Toxicol Pharmacol. 2010 Aug;152(2):232-40. Epub 2010 Apr 22. PMID: 20417311

Article Published Date : Aug 01, 2010

Study Type : Animal Study

Additional Links

Problem Substances : Triclosan : CK(13) : AC(8)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35)

"Formulated glyphosate activates the DNA-response checkpoint of the cell cycle leading to the prevention of G2/M transition."

Click here to read the entire abstract

Pubmed Data : Toxicol Sci. 2004 Dec ;82(2):436-42. Epub 2004 Sep 16. PMID: 15375296

Article Published Date : Dec 01, 2004

Study Type : In Vitro Study

Additional Links

Problem Substances : Glyphosate : CK(365) : AC(116)

Adverse Pharmacological Actions : Cell Cycle Inhibitor : CK(3) : AC(1), Cytotoxic : CK(73) : AC(35)

A commercial formulation of glyphosate inhibits proliferation and differentiation to adipocytes and induces programmed cell death in 3T3-L1 fibroblasts.

Click here to read the entire abstract

Pubmed Data : Toxicol In Vitro. 2012 Apr 21. Epub 2012 Apr 21. PMID: 22546541

Article Published Date : Apr 21, 2012

Study Type : In Vitro Study

Additional Links

Diseases : Glyphosate Toxicity : CK(22) : AC(12)

Problem Substances : Glyphosate : CK(365) : AC(116)

Adverse Pharmacological Actions : Apoptotic : CK(8) : AC(7), Cytotoxic : CK(73) : AC(35)

A glyphosate-based pesticide impinges on transcription.

Click here to read the entire abstract

Pubmed Data : Toxicol Appl Pharmacol. 2005 Feb 15 ;203(1):1-8. PMID: 15694458

Article Published Date : Feb 15, 2005

Study Type : In Vitro Study

Additional Links

Problem Substances : Glyphosate : CK(365) : AC(116), Polyoxyethylene amine : CK(12) : AC(7)

Adverse Pharmacological Actions : Cell Cycle Inhibitor : CK(3) : AC(1), Cytotoxic : CK(73) : AC(35)

Bisphenol F may have cytotoxic and allergenic properties.

Click here to read the entire abstract

Pubmed Data : Chem Res Toxicol. 2012 Nov 19 ;25(11):2469-78. Epub 2012 Oct 9. PMID: 22998141

Article Published Date : Nov 18, 2012

Study Type : Review

Additional Links

Problem Substances : Bisphenol F : CK(2) : AC(1)

Adverse Pharmacological Actions : Allergenic : CK(25) : AC(5), Cytotoxic : CK(73) : AC(35)

Bisphosphonates exhibit cytotoxicity to the bone-building cells known as osteoblasts - Article 2.

Click here to read the entire abstract

Pubmed Data : Calcif Tissue Int. 2008 Mar;82(3):191-201. Epub 2008 Feb 8. PMID: 18259679

Article Published Date : Mar 01, 2008

Study Type : In Vitro Study

Additional Links

Diseases : Osteoporosis : CK(1171) : AC(205)

Problem Substances : Alendronate (trade name Fosamax) : CK(166) : AC(27), Bisphosphonates : CK(496) : AC(61), Pamidronate (trade name Aredia) : CK(1) : AC(1)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35)

Bisphosphonates exhibit cytotoxicity to the bone-building cells known as osteoblasts.

Click here to read the entire abstract

Pubmed Data : Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Jul;106(1):5-13. Epub 2008 May 27. PMID: 18504149

Article Published Date : Jul 01, 2008

Study Type : In Vitro Study

Additional Links

Diseases : Osteoporosis : CK(1171) : AC(205)

Problem Substances : Alendronate (trade name Fosamax) : CK(166) : AC(27), Bisphosphonates : CK(496) : AC(61), Zoledronic Acid : CK(69) : AC(13)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35)

Borax exhibits cytotoxicity and genetic toxicity in human cells.

Click here to read the entire abstract

Pubmed Data : J Occup Med Toxicol. 2009;4:27. Epub 2009 Oct 30. PMID: 19878537

Article Published Date : Jan 01, 2009

Study Type : In Vitro Study

Additional Links

Diseases : DNA damage : CK(711) : AC(293)

Problem Substances : Borax (sodium borate) : CK(3) : AC(3)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35), Genotoxic : CK(146) : AC(61)

Both aluminium hydroxide and calcium phosphate exert local tissue irritating effects through damaging macrophages and increasing inflammation.

Click here to read the entire abstract

Pubmed Data : Vaccine. 1997 Aug-Sep;15(12-13):1364-71. PMID: 9302746

Article Published Date : Aug 01, 1997

Study Type : In Vitro Study

Additional Links

Problem Substances : Aluminum Hydroxide : CK(56) : AC(14), Calcium Phosphate : CK(6) : AC(4)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35), Inflammatory : CK(150) : AC(37), Irritant : CK(49) : AC(9)

BPS, once considered a safe substitute for BPA, disrupts membrane-initiated E2-induced cell signaling, leading to altered cell proliferation, cell death,and PRL release.

Click here to read the entire abstract

Pubmed Data : Environ Health Perspect. 2013 Mar ;121(3):352-8. Epub 2012 Dec 13. PMID: 23458715

Article Published Date : Feb 28, 2013

Study Type : In Vitro Study

Additional Links

Problem Substances : Bisphenol S : CK(21) : AC(9)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35), Endocrine Disruptor : CK(478) : AC(81)

Bread wheat gliadin exhibits direct and signficant cytotoxicity.

Click here to read the entire abstract

Pubmed Data : Scand J Clin Lab Invest. 2003 ;63(2):135-41. PMID: 12751695

Article Published Date : Jan 01, 2003

Study Type : In Vitro Study

Additional Links

Diseases : Gluten Intolerance : CK(236) : AC(33)

Problem Substances : Gliadin : CK(2509) : AC(110)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35)

DEET absorbs through the skin following topical application and may have significant toxicity.

Click here to read the entire abstract

Pubmed Data : J Toxicol Environ Health. 1986;18(4):503-25. PMID: 3525852

Article Published Date : Jan 01, 1986

Study Type : Commentary

Additional Links

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35), Neurotoxic : CK(1076) : AC(179)

Despite the belief that immune-mediation is required for gliadin to damage to the body, gliadin appears to directly damage the cells exposed to it; i

Click here to read the entire abstract

Pubmed Data : World J Gastroenterol. 2005 Oct 14 ;11(38):5973-7. PMID: 16273608

Article Published Date : Oct 14, 2005

Study Type : In Vitro Study

Additional Links

Diseases : Gastrointestinal Inflammation : CK(41) : AC(7), Oxidative Stress : CK(1945) : AC(710)

Problem Substances : Gliadin : CK(2509) : AC(110)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35), Oxidant : CK(104) : AC(37)

Digested formula but not digested fresh human milk causes death of intestinal cells in vitro: implications for necrotizing enterocolitis.

Click here to read the entire abstract

Pubmed Data : Pediatr Res. 2012 Dec ;72(6):560-7. Epub 2012 Sep 24. PMID: 23007028

Article Published Date : Nov 30, 2012

Study Type : In Vitro Study

Additional Links

Substances : Breast Milk : CK(428) : AC(49)

Diseases : Infant Chemical Exposures : CK(162) : AC(22), Infant Nutrition: Infant Formula : CK(278) : AC(33), Necrotising enterocolitis : CK(79) : AC(12)

Therapeutic Actions : Breastfeeding : CK(708) : AC(67)

Problem Substances : Infant Formula : CK(485) : AC(63)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35)

Ethylhexyl p-methoxycinnamate (EHMC), octyl p-dimethylaminobenzoate (PABA) and oxybenzone (OB) exhibit cytotoxicity and inhibit DNA synthesis.

Click here to read the entire abstract

Pubmed Data : Photochem Photobiol. 1999 May;69(5):611-6. PMID: 10333769

Article Published Date : May 01, 1999

Study Type : In Vitro Study

Additional Links

Diseases : DNA damage : CK(711) : AC(293)

Problem Substances : Ethylhexyl P-Methoxycinnamate (EHMC) : CK(1) : AC(1), Octyl P-Dimethylaminobenzoate (PABA) : CK(2) : AC(2), Oxybenzone : CK(30) : AC(10)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35)

Related Blogs

Cleanse, Flush, Sweat, Mobilize, Chelate, Detox...and Heal

Written by Capt. Randall

Detoxification is a nebulous term encompassing a host of therapeutic practices. Cell suffocating metals and organic toxins source oxidative stress/inflammation and have been implicated in everything from cancers and heart disease to Alzheimer's and depression.

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

Printer-friendly version
Send to friend
PDF version