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Additional Topics Details for this Page
Article Count
- 5
Cumulative Knowledge
- 9
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Quick Summary: Current access displays 2 out of 5 associated Problem Substances
Name
Cumulative Knowledge
Article Count
Focus Articles
Letrozole (trade name Femera)
4
2
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Oxybenzone
2
1
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Quick Summary: Current access displays 2 out of 7 associated Diseases
Name
Cumulative Knowledge
Article Count
Focus Articles
Prenatal Chemical Exposures
7
4
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Birth Defects
6
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View the Evidence: Adverse Pharmacological Actions
Gestational exposure to doses of letrozole that are equal to or lower than the daily recommended human dose has toxic effects on prenatal development in rats.
Click here to read the entire abstract
Pubmed Data
: Hum Reprod. 2008 Aug;23(8):1719-23. Epub 2008 May 15. PMID:
18487213
Article Published Date
: Aug 01, 2008
Study Type
: Animal Study
Additional Links
Diseases
:
Birth Defects : CK(196) : AC(37)
,
Drug-Induced Toxicity : CK(560) : AC(78)
,
Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances
:
Letrozole (trade name Femera) : CK(84) : AC(10)
Adverse Pharmacological Actions
:
Embryotoxic : CK(9) : AC(5)
,
Teratogenic : CK(304) : AC(59)
Letrozole has a toxic effect on the embryos of rats.
Click here to read the entire abstract
Pubmed Data
: Hum Reprod. 2009 Nov;24(11):2688-92. Epub 2009 Jul 27. PMID:
19638353
Article Published Date
: Nov 01, 2009
Study Type
: Animal Study
Additional Links
Diseases
:
Abortion: Spontaneous : CK(204) : AC(29)
,
Birth Defects : CK(196) : AC(37)
,
Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances
:
Letrozole (trade name Femera) : CK(84) : AC(10)
Adverse Pharmacological Actions
:
Embryotoxic : CK(9) : AC(5)
,
Teratogenic : CK(304) : AC(59)
Oxybenzone (an active ingredient in sunscreen) exhibit estrogenic and reproductive effects in fish.
Click here to read the entire abstract
Pubmed Data
: Aquat Toxicol. 2008 Nov 21;90(3):182-7. Epub 2008 Sep 10. PMID:
18930325
Article Published Date
: Nov 21, 2008
Study Type
: Animal Study
Additional Links
Diseases
:
Childhood Chemical Exposures : CK(155) : AC(17)
,
Infant Chemical Exposures : CK(162) : AC(22)
,
Prenatal Chemical Exposures : CK(322) : AC(86)
Additional Keywords
:
Environmental Pollutant : CK(32) : AC(15)
Problem Substances
:
Oxybenzone : CK(30) : AC(10)
Adverse Pharmacological Actions
:
Embryotoxic : CK(9) : AC(5)
,
Estrogenic : CK(59) : AC(12)
The diethylamine salt of 2,4-D exhibits embryotoxic actions.
Click here to read the entire abstract
Pubmed Data
: Gig Sanit. 1973 Feb ;38(2):100-1. PMID:
4779861
Article Published Date
: Feb 01, 1973
Study Type
: Animal Study
Additional Links
Diseases
:
Birth Defects : CK(196) : AC(37)
,
Miscarriage : CK(507) : AC(35)
Problem Substances
:
2
Adverse Pharmacological Actions
:
Embryotoxic : CK(9) : AC(5)
Warfarin and lovastatin exhibit embryotoxic potential.
Click here to read the entire abstract
Pubmed Data
: Reprod Toxicol. 2010 Aug;30(1):121-30. Epub 2010 May 20. PMID:
20493250
Article Published Date
: Aug 01, 2010
Study Type
: In Vitro Study
Additional Links
Diseases
:
Prenatal Chemical Exposures : CK(322) : AC(86)
Problem Substances
:
Lovastatin : CK(265) : AC(67)
,
Warfarin : CK(251) : AC(27)
Adverse Pharmacological Actions
:
Embryotoxic : CK(9) : AC(5)
,
Teratogenic : CK(304) : AC(59)
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