Excitotoxic

Excitotoxic

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Article Count - 1
Cumulative Knowledge - 12

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Cumulative Knowledge is determined by ascribing a numerical value to the various study types weighted in descending order as follows: (1) Meta-Analysis; (2) Human Study; (3) Human: Case Study; (4) Animal: Transgenic; (5) Animal; (6) In Vitro; (7) Review; and (8) Commentary.

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Quick Summary: 2 associated Problem Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
L-glutamic Acid	10	1	Log in \| Sign up
Monosodium Glutamate (MSG)	10	1	Log in \| Sign up

Quick Summary: 1 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Amyotrophic Lateral Sclerosis	10	1	Log in \| Sign up

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View the Evidence: Adverse Pharmacological Actions

Glutamate levels may contribute to the pathogenesis of ALS.

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Pubmed Data : Acta Neurol Scand. 2010 Feb;121(2):120-6. Epub 2009 Oct 5. PMID: 19804473

Article Published Date : Feb 01, 2010

Study Type : Human Study

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Diseases : Amyotrophic Lateral Sclerosis : CK(350) : AC(68)

Problem Substances : L-glutamic Acid : CK(11) : AC(2), Monosodium Glutamate (MSG) : CK(39) : AC(12)

Adverse Pharmacological Actions : Excitotoxic : CK(10) : AC(1)

Glutamate induces mitochondrial dynamic imbalance and autophagy activation that can be prevented with selenium.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2012 ;7(6):e39382. Epub 2012 Jun 19. PMID: 22724008

Article Published Date : Dec 31, 2011

Study Type : Animal Study

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Substances : Selenium : CK(574) : AC(94)

Diseases : Excitotoxicity : CK(56) : AC(33)

Pharmacological Actions : Neuroprotective Agents : CK(962) : AC(480)

Problem Substances : L-glutamic Acid : CK(11) : AC(2), Monosodium Glutamate (MSG) : CK(39) : AC(12)

Adverse Pharmacological Actions : Excitotoxic : CK(10) : AC(1)

Related Blogs

MSG: Delicious Seasoning Or Drug And Poison?

Written by Sayer Ji, Founder

Monosodium glutamate (MSG) is a commonly used "flavor enhancer," and so powerfully so that (arguably) you could spray it on roadkill and it would taste good. This omnipresent ingredient in modern mass market food takes advantage of our biologically hard-wired taste receptors, and makes it very hard to stop eating the foods "seasoned" with this ingredient.

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