Download Now

Your Token Count

0

Sign in to Purchase/Download Documents

Sign in / Register

User login

Social Networking

Support Free Media

Teratogenic

User Options

A Membership is required. Please Login or Create an account to get started

Request us to build a Downloadable Document Product on this Topic

Make a Request for GMI to add more Articles on this Topic Immediately (Purchase Required)

View a Printer Friendly version of this page

E-mail this page to a friend

Perform a Search with this Topic

Hover over an icon for more information

Additional Topics Details for this Page

Article Count - 59
Cumulative Knowledge - 306

Advanced Database Options

Limit Articles Displayed by the Following Study Types

Available Sorting Options

Limited to Members Only

By default, all articles on GreenMedInfo.com are sorted based on the content type which best reflects the data which most users are searching for. For instance, people viewing substances are generally most interested in viewing diseases that these substances have shown to have positive influences. This section is for allowing more advanced sorting methods. Currently, these advanced sorting methods are available for members only. If you are already a member, you can sign in by clicking here. If you do not currently have a user account, and would like to create one/become a member, click here to begin the singup process.

Currently Available Sorting Options

Article Published Date - Sort all displayed articles by their published date
Quick Summary Fieldsets - Sort alphabetically, rather than by Cumulative Knowledge
Cumulative Knowledge - Default sorting method. Allows you to sort descendingly

What is Cumulative Knowledge?

Cumulative Knowledge is determined by ascribing a numerical value to the various study types weighted in descending order as follows: (1) Meta-Analysis; (2) Human Study; (3) Human: Case Study; (4) Animal: Transgenic; (5) Animal; (6) In Vitro; (7) Review; and (8) Commentary.

Click here for a more thorough explanation.

Quick Summary: Current access displays 2 out of 52 associated Problem Substances

Name	Cumulative Knowledge	Article Count	Focus Articles
Coffee	52	5	Log in \| Sign up
Caffeine	40	4	Log in \| Sign up

Quick Summary: Current access displays 2 out of 43 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Abortion: Spontaneous	140	16	Log in \| Sign up
Miscarriage	124	14	Log in \| Sign up

Currently Viewing Free Sample of Member Only Features

Although all 19,000+ articles on GreenMedInfo.com are made entirely free to view as an educational service to the public, we provide a powerful set of enhanced data comprehension and retrieval tools for subscribing members. Above you are viewing a free preview, limited to 2 rows, of the membership feature called "Cumulative Knowledge" (learn more).

The Focus Article Feature is not enabled.

Upgrading to the Member role gives you access to unlimited rows of Cumulative Knowledge data.

To Participate

Click here to login
Click here to create an account

View the Evidence: Adverse Pharmacological Actions

Consumption of coffee during pregnancy was associated with a higher risk of fetal death, especially losses occurring after 20 completed weeks of gestation.

Click here to read the entire abstract

Pubmed Data : Am J Epidemiol. 2005 Nov 15;162(10):983-90. Epub 2005 Oct 5. PMID: 16207803

Article Published Date : Nov 15, 2005

Study Type : Meta Analysis

Additional Links

Diseases : Abortion: Spontaneous : CK(204) : AC(29), Fetal Death : CK(30) : AC(2), Miscarriage : CK(507) : AC(35)

Problem Substances : Coffee : CK(64) : AC(7)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Recurrent miscarriages may occur due to undiagnosed celiac disease, and may resolve after a gluten-free diet.

Click here to read the entire abstract

Pubmed Data : Dig Dis Sci. 2008 Nov;53(11):2925-8. Epub 2008 Mar 27. PMID: 18368491

Article Published Date : Nov 01, 2008

Study Type : Meta Analysis

Additional Links

Diseases : Celiac Disease : CK(1527) : AC(215), Gluten Intolerance : CK(236) : AC(33), Wheat Intolerance : CK(2480) : AC(231)

Problem Substances : Gluten : CK(1755) : AC(144), Wheat : CK(2542) : AC(309)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Birth defects are more common in pregnant women who received the anthrax vaccine during their first trimester versus later in pregnancy.

Click here to read the entire abstract

Pubmed Data : Am J Epidemiol. 2008 Aug 15 ;168(4):434-42. Epub 2008 Jul 2. PMID: 18599489

Article Published Date : Aug 15, 2008

Study Type : Human Study

Additional Links

Diseases : Anthrax : CK(43) : AC(6), Birth Defects : CK(196) : AC(37), Vaccine-induced Toxicity : CK(1130) : AC(163)

Anti Therapeutic Actions : Vaccination: All : CK(3830) : AC(302), Vaccination: Anthrax : CK(62) : AC(8)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Celiac disease associated antibodies are higher in Argentine women with recurrent pregnancy loss.

Click here to read the entire abstract

Pubmed Data : Am J Reprod Immunol. 2006 Mar;55(3):201-7. PMID: 16451354

Article Published Date : Mar 01, 2006

Study Type : Human Study

Additional Links

Diseases : Abortion: Spontaneous : CK(204) : AC(29), Miscarriage: Recurrent : CK(21) : AC(3)

Problem Substances : Gliadin : CK(2509) : AC(110), Wheat : CK(2542) : AC(309)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Coffee drinking early in pregnancy is associated with an increased risk of abortion.

Click here to read the entire abstract

Pubmed Data : Hum Reprod. 1998 Aug;13(8):2286-91. PMID: 9756312

Article Published Date : Aug 01, 1998

Study Type : Human Study

Additional Links

Diseases : Abortion: Spontaneous : CK(204) : AC(29), Miscarriage : CK(507) : AC(35)

Problem Substances : Coffee : CK(64) : AC(7)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Environmental tobacco smoke increases the risk of spontaneous abortion.

Click here to read the entire abstract

Pubmed Data : Epidemiology. 2006 Sep;17(5):500-5. PMID: 16837826

Article Published Date : Sep 01, 2006

Study Type : Human Study

Additional Links

Diseases : Abortion: Spontaneous : CK(204) : AC(29), Miscarriage : CK(507) : AC(35)

Problem Substances : Tobacco Smoke: Passive : CK(31) : AC(4)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Heavy caffeine consumption (especially when there is nausea) during pregnancy may increase the risk of spontaneous abortion.

Click here to read the entire abstract

Pubmed Data : Epidemiology. 1991 May;2(3):168-74. PMID: 2054397

Article Published Date : May 01, 1991

Study Type : Human Study

Additional Links

Diseases : Abortion: Spontaneous : CK(204) : AC(29), Miscarriage : CK(507) : AC(35)

Problem Substances : Caffeine : CK(70) : AC(7)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

High dietary intake of preformed vitamin A appears to be teratogenic. Among the babies born to women who took more than 10,000 IU of preformed vitamin A per day in the form of supplements, we estimate that about 1 infant in 57 had a malformation attributa

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : N Engl J Med. 1995 Nov 23 ;333(21):1369-73. PMID: 7477116

Article Published Date : Nov 23, 1995

Study Type : Human Study

Additional Links

Substances : Vitamin A : CK(371) : AC(58)

Diseases : Abnormalities, Birth Defects : CK(196) : AC(37), Drug-Induced, Prenatal Nutrition: Prevention of Problems : CK(357) : AC(41)

Problem Substances : Retinyl palmitate : CK(17) : AC(5)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Human epidemiological evidence is consistent with increased risk of birth defects in offspring of persons exposed to depleted uranium.

Click here to read the entire abstract

Pubmed Data : Environ Health. 2005;4:17. Epub 2005 Aug 26. PMID: 16124873

Article Published Date : Jan 01, 2005

Study Type : Human Study

Additional Links

Diseases : Birth Defects : CK(196) : AC(37)

Problem Substances : Uranium: Depleted : CK(22) : AC(11)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Increased risk of adverse pregnancy outcomes in women receiving zolpidem during pregnancy.

Click here to read the entire abstract

Pubmed Data : Clin Pharmacol Ther. 2010 Sep;88(3):369-74. Epub 2010 Aug 4. PMID: 20686480

Article Published Date : Sep 01, 2010

Study Type : Human Study

Additional Links

Diseases : Pregnancy Complications : CK(166) : AC(19), Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Zolpidem (trade name Ambien) : CK(199) : AC(25)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Maternal caffeine consumption has been linked to neural tube defects.

Click here to read the entire abstract

Pubmed Data : Birth Defects Res A Clin Mol Teratol. 2009 Nov;85(11):879-89. PMID: 19711421

Article Published Date : Nov 01, 2009

Study Type : Human Study

Additional Links

Diseases : Neural Tube Defects : CK(10) : AC(1), Prenatal Nutrition: Health of the Offspring : CK(224) : AC(31), Spina Bifida : CK(20) : AC(2)

Problem Substances : Caffeine : CK(70) : AC(7)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Maternal caffeine consumption is associated with an increased risk of spontaneous abortion.

Click here to read the entire abstract

Pubmed Data : Epidemiology. 1996 May;7(3):250-5. PMID: 8728437

Article Published Date : May 01, 1996

Study Type : Human Study

Additional Links

Diseases : Abortion: Spontaneous : CK(204) : AC(29), Miscarriage : CK(507) : AC(35)

Problem Substances : Caffeine : CK(70) : AC(7), Coffee : CK(64) : AC(7), Tea : CK(10) : AC(1)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Maternal exposure to occupational hazards associated with radiation, pesticides and anesthetic gases (e.g. veterinary practice) is associated with an increased risk of spontaneous abortions.

Click here to read the entire abstract

Pubmed Data : Occup Environ Med. 2008 Nov;65(11):719-25. Epub 2008 Apr 3. PMID: 18388114

Article Published Date : Nov 01, 2008

Study Type : Human Study

Additional Links

Diseases : Abortion: Spontaneous : CK(204) : AC(29), Miscarriage : CK(507) : AC(35)

Problem Substances : Anaesthetic Gases : CK(10) : AC(1), Pesticides : CK(699) : AC(70), Radiation Exposure : CK(11) : AC(2)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Newborns exposed in utero to SSRIs, have a twofold higher risk of mild nonsyndromic heart defects than unexposed infants.

Click here to read the entire abstract

Pubmed Data : Birth Defects Res A Clin Mol Teratol. 2009 Oct;85(10):837-41. PMID: 19691085

Article Published Date : Oct 01, 2009

Study Type : Human Study

Additional Links

Diseases : Heart Defects: Congenital : CK(10) : AC(1), Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Fluoxetine (trade name Prozac) : CK(79) : AC(21), Selective Serotonin Reuptake Inhibitors (SSRIs) : CK(74) : AC(9)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Risk documentation occured in only 20% of women age 15-45 prescribed a medication known to contribute to birth defects.

Click here to read the entire abstract

Pubmed Data : J Am Board Fam Med. 2011 May-Jun;24(3):262-71. PMID: 21551398

Article Published Date : May 01, 2011

Study Type : Human Study

Additional Links

Diseases : Birth Defects : CK(196) : AC(37), Drug-Induced Toxicity : CK(560) : AC(78), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Angiotensin-Converting Enzyme (ACE) Inhibitor : CK(70) : AC(7), Angiotensin Receptor Blockers (ARBs) : CK(20) : AC(2), Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Taking non-aspirin NSAIDs in early pregnancy doubles the risk of miscarriage.

Click here to read the entire abstract

Pubmed Data : BMJ. 2011 ;343:d5769. Epub 2011 Sep 9. PMID: 21908536

Article Published Date : Jan 01, 2011

Study Type : Human Study

Additional Links

Diseases : Abortion: Spontaneous : CK(204) : AC(29), Drug-Induced Toxicity : CK(560) : AC(78), Miscarriage : CK(507) : AC(35)

Pharmacological Actions : Teratogens : CK(10) : AC(1)

Problem Substances : Celecoxib : CK(50) : AC(4), Diclofenac : CK(72) : AC(7), Ibuprofen : CK(162) : AC(19), Naproxen : CK(54) : AC(7), Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) : CK(1383) : AC(115), Rofecoxib : CK(60) : AC(5)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

The ingestion of caffeine may increase the risk of an early spontaneous abortion among non-smoking women carrying fetuses with normal karyotypes.

Click here to read the entire abstract

Pubmed Data : N Engl J Med. 2000 Dec 21;343(25):1839-45. PMID: 11117975

Article Published Date : Dec 21, 2000

Study Type : Human Study

Additional Links

Diseases : Abortion: Spontaneous : CK(204) : AC(29), Miscarriage : CK(507) : AC(35)

Problem Substances : Caffeine : CK(70) : AC(7)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Transplacental polycyclic aromatic hydrocarbons exposure to the fetus is compromising fetal development.

Click here to read the entire abstract

Pubmed Data : Environ Health Perspect. 1999 Jun;107 Suppl 3:451-60. PMID: 10346993

Article Published Date : Jun 01, 1999

Study Type : Human Study

Additional Links

Diseases : DNA damage : CK(711) : AC(293), Prenatal Chemical Exposures : CK(322) : AC(86)

Problem Substances : Polycyclic aromatic hydrocarbon : CK(13) : AC(4)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Unexplained infertility in women may be due to celiac disease.

Click here to read the entire abstract

Pubmed Data : Minerva Med. 2007 Jun;98(3):217-9. PMID: 17592443

Article Published Date : Jun 01, 2007

Study Type : Human Study

Additional Links

Diseases : Celiac Disease : CK(1527) : AC(215), Infertility : CK(455) : AC(94), Infertility: Female : CK(182) : AC(33), Wheat Intolerance : CK(2480) : AC(231)

Problem Substances : Gliadin : CK(2509) : AC(110), Gluten : CK(1755) : AC(144), Wheat : CK(2542) : AC(309)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Use of non-steroidal anti-inflammatory drugs during pregnancy is associated with increased risk of miscarriage.

Click here to read the entire abstract

Pubmed Data : BMJ. 2001 Feb 3;322(7281):266-70. PMID: 11157526

Article Published Date : Feb 03, 2001

Study Type : Human Study

Additional Links

Diseases : Abortion: Spontaneous : CK(204) : AC(29), Miscarriage : CK(507) : AC(35)

Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) : CK(1383) : AC(115)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Use of pivmecillinam (antibiotic) is associated with an increased risk of miscarriage.

Click here to read the entire abstract

Pubmed Data : APMIS. 2008 Apr;116(4):278-83. PMID: 18397462

Article Published Date : Apr 01, 2008

Study Type : Human Study

Additional Links

Diseases : Abortion: Spontaneous : CK(204) : AC(29), Female Urogenital Diseases and Pregnancy Complications : CK(10) : AC(1), Miscarriage : CK(507) : AC(35), Pregnancy Complications : CK(166) : AC(19), Pregnancy Complications: Urinary Tract Infections : CK(10) : AC(1), Prenatal Chemical Exposures : CK(322) : AC(86)

Additional Keywords : Antibiotic Use in Pregnancy : CK(10) : AC(1)

Problem Substances : Antibiotics : CK(180) : AC(19), Pivmecillinam : CK(10) : AC(1)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Lovastatin exhibits toxicity in human fetal brain cells.

Click here to read the entire abstract

Pubmed Data : Neurotoxicol Teratol. 1995 Jan-Feb;17(1):31-9. PMID: 7708017

Article Published Date : Jan 01, 1995

Study Type : Human In Vitro

Additional Links

Diseases : Abortion: Spontaneous : CK(204) : AC(29), Birth Defects : CK(196) : AC(37), Neurotoxicity : CK(37) : AC(15), Prenatal Chemical Exposures : CK(322) : AC(86)

Pharmacological Actions : Antiproliferative : CK(1052) : AC(775)

Problem Substances : Lovastatin : CK(265) : AC(67)

Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179), Teratogenic : CK(304) : AC(59)

Central nervous system and limb anomalies have been reported in first-trimester statin exposure.

Click here to read the entire abstract

Pubmed Data : N Engl J Med. 2004 Apr 8 ;350(15):1579-82. PMID: 15071140

Article Published Date : Apr 08, 2004

Study Type : Human: Case Report

Additional Links

Diseases : Birth Defects : CK(196) : AC(37), Pregnancy: Environmental Exposures : CK(29) : AC(6), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Gestational exposure to lovastatin followed by cardiac malformation misclassified as holoprosencephaly has been reported.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : N Engl J Med. 2005 Jun 30 ;352(26):2759. PMID: 15987932

Article Published Date : Jun 30, 2005

Study Type : Human: Case Report

Additional Links

Diseases : Birth Defects : CK(196) : AC(37), Pregnancy: Environmental Exposures : CK(29) : AC(6), Statin-Induced Pathologies : CK(1570) : AC(315)

Problem Substances : Lovastatin : CK(265) : AC(67), Statin Drugs : CK(3969) : AC(465)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

High-dose methotrexate during pregnancy is associated malformations.

Click here to read the entire abstract

Pubmed Data : Prescrire Int. 2010 Oct;19(109):212-3. PMID: 21180376

Article Published Date : Oct 01, 2010

Study Type : Human: Case Report

Additional Links

Diseases : Birth Defects : CK(196) : AC(37), Cardiomyopathy : CK(77) : AC(15), Drug Toxicity: Methotrexate : CK(30) : AC(13), Prenatal Chemical Exposures : CK(322) : AC(86), Scoliosis : CK(111) : AC(13)

Problem Substances : Methotrexate : CK(11) : AC(3)

Adverse Pharmacological Actions : Teratogenic : CK(304) : AC(59)

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

Printer-friendly version
Send to friend
PDF version