High Bone Density

High Bone Density

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View the Evidence: Problematic Actions

Bone mineral density is a significant prognostic factor for postmenopausal Caucasian women with breast cancer. Low bone mineral density is associated with a lower local and distant rate of recurrence.

Pubmed Data : Breast J. 2013 Mar-Apr;19(2):168-72. Epub 2013 Feb 13. PMID: 23406171
Article Published Date : Feb 28, 2013
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2354) : AC(621), Osteoporosis : CK(1171) : AC(205)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

Elderly women with high bone mineral density (BMD) have up to 2.7 times greater risk of breast cancer, especially advanced cancer, compared with women with low BMD.

Pubmed Data : J Natl Cancer Inst. 2001 Jun 20;93(12):930-6. PMID: 11416114
Article Published Date : Jun 20, 2001
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2354) : AC(621), Obesity : CK(1849) : AC(275), Osteoporosis : CK(1171) : AC(205)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

Higher bone density (upper 33%) is associated with a 2-fold increased risk of breast cancer.

Pubmed Data : Bone. 2003 Mar;32(3):211-6. PMID: 12667548
Article Published Date : Mar 01, 2003
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2354) : AC(621), Osteoporosis : CK(1171) : AC(205)
Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

Higher bone density is associated wtih higher endometrial thickness.

Pubmed Data : Gynecol Endocrinol. 2010 Feb 23. Epub 2010 Feb 23. PMID: 20175708
Article Published Date : Feb 23, 2010
Study Type : Human Study
Additional Links
Diseases : Endometrial Cancer : CK(269) : AC(45)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

Higher bone mass is associated with greater risk for breast cancer.

Pubmed Data : Maturitas. 2007 Mar 20;56(3):312-21. Epub 2006 Oct 17. PMID: 17049767
Article Published Date : Mar 20, 2007
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2354) : AC(621), Osteoporosis : CK(1171) : AC(205)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

Higher bone mineral density is associated with higher incidence of estrogen receptor positive breast cancer.

Pubmed Data : Maturitas. 2007 Jul 20;57(3):221-5. Epub 2007 Jan 19. PMID: 17240090
Article Published Date : Jul 20, 2007
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2354) : AC(621), Osteoporosis : CK(1171) : AC(205)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

Increase in lumbar spine and femoral neck bone mineral density is associated with a 2.1 fold and 1.5 fold respectively, higher risk of breast cancer.

Pubmed Data : Maturitas. 2000 Jul 31;36(1):27-34. PMID: 10989239
Article Published Date : Jul 31, 2000
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2354) : AC(621), Osteoporosis : CK(1171) : AC(205)
Additional Keywords : Breast : CK(10) : AC(1)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

Mammographic breast density is inversely associated with bone mineral density in the perimenopausal women.

Pubmed Data : Ann Epidemiol. 2007 Aug;17(8):575-83. Epub 2007 May 29. PMID: 17532645
Article Published Date : Aug 01, 2007
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2354) : AC(621), Osteoporosis : CK(1171) : AC(205)
Additional Keywords : Diseases that are Linked : CK(2122) : AC(270)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

There is higher BMD irrespective of the method and site of measurement in postmenopausal women with breast cancer compared to controls.

Pubmed Data : Climacteric. 2011 Jun ;14(3):352-61. Epub 2011 Mar 17. PMID: 21413864
Article Published Date : Jun 01, 2011
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2354) : AC(621)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

Tibolone increases bone mineral density but also relapse in breast cancer survivors. This increase in breast cancer was not seen in those women with low BMD.

Pubmed Data : Breast Cancer Res. 2012 Jan 17 ;14(1):R13. Epub 2012 Jan 17. PMID: 22251615
Article Published Date : Jan 17, 2012
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2354) : AC(621)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)
Problem Substances : Hormone Replacement Therapy : CK(81) : AC(6), Hormone Replacement Therapy: Tibolone : CK(10) : AC(1)
Adverse Pharmacological Actions : Carcinogenic : CK(912) : AC(117)

Women in the lowest quartile of bone mass appear to be protected against breast cancer.

Pubmed Data : Breast. 2001 Aug;10(4):313-7. PMID: 14965600
Article Published Date : Aug 01, 2001
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2354) : AC(621), Osteoporosis : CK(1171) : AC(205)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

Women with a positive family history of breast cancer and who are in the highest tertile bone mineral density are at a 3.41-fold increased risk compared with women in the lowest tertile.

Pubmed Data : Am J Epidemiol. 1998 Jul 1;148(1):22-9. PMID: 9663400
Article Published Date : Jul 01, 1998
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2354) : AC(621), Osteoporosis : CK(1171) : AC(205)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

Women with bone mineral density above the 25th percentile have 2.0 to 2.5 times increased risk of breast cancer compared with women below the 25th percentile.

Pubmed Data : JAMA. 1996 Nov 6;276(17):1404-8. PMID: 8892715
Article Published Date : Nov 06, 1996
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2354) : AC(621), Osteoporosis : CK(1171) : AC(205)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

Women with highest tertile bone mineral density (BMD) measured at the Ward's triangle and at the femoral neck are respectively at 2.2-and 3.3-fold increased risk of breast cancer compared with women at the lowest tertile of BMD.

Pubmed Data : Eur J Epidemiol. 2004;19(8):785-92. PMID: 15469036
Article Published Date : Jan 01, 2004
Study Type : Human Study
Additional Links
Diseases : Breast Cancer : CK(2354) : AC(621), Osteoporosis : CK(1171) : AC(205)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

Individuals with certain diseases such as obesity, diabetes, estrogen receptor-positive breast or endometrial cancer have greater bone density than healthy individuals,

Pubmed Data : Endocrinol Nutr. 2012 Mar ;59(3):207-14. Epub 2012 Feb 9. PMID: 22325788
Article Published Date : Mar 01, 2012
Study Type : Review
Additional Links
Diseases : Breast Cancer: Estrogen : CK(5) : AC(2), Diabetes, Endometrial Cancer : CK(269) : AC(45), Obesity : CK(1849) : AC(275)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

Postmenopausal women in the highest quartile for metacarpal bone mass were found to have an increased risk of developing breast cancer, after adjusting for age and other variables known to influence breast cancer risk.

Pubmed Data : Nutr Rev. 1997 Jul;55(7):284-6. PMID: 9279067
Article Published Date : Jul 01, 1997
Study Type : Commentary
Additional Links
Diseases : Breast Cancer : CK(2354) : AC(621), Osteoporosis : CK(1171) : AC(205)
Anti Therapeutic Actions : High Bone Density : CK(142) : AC(16)

Related Blogs

Why Having 'Normal' or 'High' Bone Density is Bad For Your Health
Written by Sayer Ji, Founder
Over the past two decades, millions of older women have been pressured into thinking that if their bones are not as dense as a 30-year old that they have a 'medical condition' treatable with megadose calcium supplements and bone-targeting drugs. And yet, research indicates that this new definition of 'normal,' which has disingenously redefined the natural thinning of the bones that comes with age as a disease, is actually a risk factor for breast cancer, and worsened...
Stoned To Death: Calcium Supplements Proven To Kill Again
Written by Sayer Ji, Founder
New research published this week in the journal Heart has confirmed the findings of two controversial studies on calcium supplementation and heart attack risk published in the British Medical Journal last year, and which found a 24-27% increased risk of heart attack for those who took 500 mg of elemental calcium a day.
The Calcium Supplement Problem: As Serious As A Heart Attack
Written by Sayer Ji, Founder
Osteoporosis is not caused by a lack of limestone, oyster shell or bone meal. Heart attack, however, may be caused by an excess consumption of exactly these "elemental" forms of calcium, according to two high-powered meta-analyses published last year in the British Medical Journal.

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