Intrapartum Antibiotics: Group B Streptococcus

Intrapartum Antibiotics: Group B Streptococcus

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Article Count - 12
Cumulative Knowledge - 149

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Quick Summary: Current access displays 2 out of 9 associated Diseases

Name	Cumulative Knowledge	Article Count	Focus Articles
Streptococcus infections: Group B	126	10	Log in \| Sign up
Neonatal group B streptococcal (GBS) infections	93	7	Log in \| Sign up

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View the Evidence: Problematic Actions

Early-onset neonatal group B streptococcal infections in New Zealand 1998-1999 were associated with young maternal age, parity, preterm labour, prolonged membrane rupture, maternal fever and assisted delivery as risk factors. Of the 56 cases, five (9%) w

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Pubmed Data : J Paediatr Child Health. 2002 Jun;38(3):272-7. PMID: 12047696

Article Published Date : Jun 01, 2002

Study Type : Meta Analysis

Additional Links

Diseases : Neonatal group B stretpococcal (GBS) infections : CK(60) : AC(3), Streptococcus infections: Group B : CK(289) : AC(21)

Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316)

Anti Therapeutic Actions : Intrapartum Antibiotics: Group B Streptococcus : CK(169) : AC(12)

Trial Results: In a sample of 67360 infants, 82% of those mothers whose term infants developed persistent early-onset GBS disease had been screened GBS negative.

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Pubmed Data : Pediatrics. 2005 May;115(5):1240-6. PMID: 15867030

Article Published Date : May 01, 2005

Study Type : Meta Analysis

Additional Links

Diseases : Neonatal group B stretpococcal (GBS) infections : CK(60) : AC(3)

Anti Therapeutic Actions : Intrapartum Antibiotics: Group B Streptococcus : CK(169) : AC(12)

Universal screening and antibiotic prophylaxis of all group B streptococcus carriers result in increased antibiotic exposure in our population, which might carry its own risks.

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Pubmed Data : Can Fam Physician. 2007 Jun;53(6):1055, 2001:e.1-6, 1054. PMID: 17872785

Article Published Date : Jun 01, 2007

Study Type : Meta Analysis

Additional Links

Diseases : Neonatal group B streptococcal (GBS) infections : CK(289) : AC(21)

Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316)

Anti Therapeutic Actions : Intrapartum Antibiotics: Group B Streptococcus : CK(169) : AC(12)

Vaginal chlorhexidine during labour does not appear to prevent adverse outcomes associated with early-onset neonatal group B streptococcal colonization.

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Pubmed Data : Cochrane Database Syst Rev. 2004(3):CD003520. PMID: 15266490

Article Published Date : Jan 01, 2004

Study Type : Meta Analysis

Additional Links

Diseases : Streptococcus infections: Group B : CK(289) : AC(21)

Anti Therapeutic Actions : Intrapartum Antibiotics: Group B Streptococcus : CK(169) : AC(12)

While intrapartum antibiotics for Group B streptococcus reduces infant colonization it does not reduce infant mortality.

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Pubmed Data : Cochrane Database Syst Rev. 2010(1):CD000115. Epub 2010 Jan 20. PMID: 20091501

Article Published Date : Jan 01, 2010

Study Type : Meta Analysis

Additional Links

Diseases : Neonatal group B streptococcal (GBS) infections : CK(289) : AC(21), Streptococcus infections: Group B : CK(289) : AC(21)

Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316)

Anti Therapeutic Actions : Intrapartum Antibiotics: Group B Streptococcus : CK(169) : AC(12)

Late onset Serious Bacterial Infections exhibiting antibiotic-resistance are more likely to occur to infants who received intrapartum antibiotics.

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Pubmed Data : Pediatrics. 2005 Sep;116(3):696-702. PMID: 16140710

Article Published Date : Sep 01, 2005

Study Type : Human Study

Additional Links

Diseases : Neonatal group B streptococcal (GBS) infections : CK(289) : AC(21), Streptococcus infections: Group B : CK(289) : AC(21)

Anti Therapeutic Actions : Intrapartum Antibiotics: Group B Streptococcus : CK(169) : AC(12)

Prenatal antibiotic treatment does not decrease group B streptococcus colonization at delivery.

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Pubmed Data : Int J Gynaecol Obstet. 2008 May;101(2):125-8. Epub 2007 Dec 20. PMID: 18082163

Article Published Date : May 01, 2008

Study Type : Human Study

Additional Links

Diseases : Neonatal group B streptococcal (GBS) infections : CK(289) : AC(21), Streptococcus infections: Group B : CK(289) : AC(21)

Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316)

Additional Keywords : Drug: Amoxicillin : CK(60) : AC(6)

Anti Therapeutic Actions : Intrapartum Antibiotics: Group B Streptococcus : CK(169) : AC(12)

Short durations of intrapartum prophylaxis may be superior to those exposed to longer durations.

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Pubmed Data : Obstet Gynecol. 2008 Aug;112(2 Pt 1):265-70. PMID: 18669721

Article Published Date : Aug 01, 2008

Study Type : Human Study

Additional Links

Diseases : Neonatal group B streptococcal (GBS) infections : CK(289) : AC(21), Streptococcus infections: Group B : CK(289) : AC(21)

Additional Keywords : Drug: Penicillin : CK(23) : AC(3), Less is More : CK(21) : AC(3)

Anti Therapeutic Actions : Intrapartum Antibiotics: Group B Streptococcus : CK(169) : AC(12)

Universal administration of penicillin to neonates shortly after birth (postpartum prophylaxis) reduces the early-onset GBS attack rate by 68% but is associated with a 40% increase in overall mortality and therefore is contraindicated.

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Pubmed Data : Pediatrics. 1999 Jun;103(6):e78. PMID: 10353975

Article Published Date : Jun 01, 1999

Study Type : Human Study

Additional Links

Diseases : Infant Mortality : CK(229) : AC(23), Streptococcus infections: Group B : CK(289) : AC(21)

Anti Therapeutic Actions : Intrapartum Antibiotics: Group B Streptococcus : CK(169) : AC(12)

A 39-year-old woman with rheumatoid arthritis developed intrapartum anaphylaxis that led to fetal demise.

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Pubmed Data : Ann Allergy Asthma Immunol. 2007 Sep;99(3):287-9. PMID: 17910335

Article Published Date : Sep 01, 2007

Study Type : Human: Case Report

Additional Links

Diseases : Rheumatoid Arthritis : CK(424) : AC(64), Streptococcus infections: Group B : CK(289) : AC(21)

Anti Therapeutic Actions : Intrapartum Antibiotics: Group B Streptococcus : CK(169) : AC(12)

Clindamycin-resistant group B Streptococcus and failure of intrapartum prophylaxis to prevent early-onset disease has been reported.

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Pubmed Data : J Pediatr. 2010 Mar;156(3):501-3. Epub 2010 Jan 13. PMID: 20056242

Article Published Date : Mar 01, 2010

Study Type : Human: Case Report

Additional Links

Diseases : Infant Infections : CK(420) : AC(45), Infection: Antibiotic Resistant : CK(303) : AC(88), Neonatal group B streptococcal (GBS) infections : CK(289) : AC(21)

Anti Therapeutic Actions : Intrapartum Antibiotics: Group B Streptococcus : CK(169) : AC(12)

Maternal anaphylaxis and fetal brain damage after intrapartum chemoprophylaxis has been reported.

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Pubmed Data : J Perinat Med. 2004;32(4):375-7. PMID: 15346827

Article Published Date : Jan 01, 2004

Study Type : Human: Case Report

Additional Links

Diseases : Anaphylaxis : CK(54) : AC(15), Antibiotic Toxicity : CK(45) : AC(11), Streptococcus infections: Group B : CK(289) : AC(21)

Pharmacological Actions : Anti-Bacterial Agents : CK(970) : AC(316)

Additional Keywords : Drug: Penicillin : CK(23) : AC(3)

Anti Therapeutic Actions : Intrapartum Antibiotics: Group B Streptococcus : CK(169) : AC(12)

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