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Article Count - 28
Cumulative Knowledge - 67

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View the Evidence: Problematic Actions

Oral administration of titanium dioxide results in gastro-intestinal absorption and increases in blood levels.

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Pubmed Data : Pharmazie. 2000 Feb;55(2):140-3. PMID: 10723775

Article Published Date : Feb 01, 2000

Study Type : Human Study

Additional Links

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Titanium Dioxide : CK(41) : AC(17)

Topical microfine titanium dioxide from sunscreens is capable of accumulating in the epidermis and dermis of humans subjects.

Click here to read the entire abstract

Pubmed Data : Australas J Dermatol. 1996 Nov;37(4):185-7. PMID: 8961584

Article Published Date : Nov 01, 1996

Study Type : Human Study

Additional Links

Diseases : Chemical Exposure : CK(49) : AC(15)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Sunscreen : CK(71) : AC(14), Titanium Dioxide : CK(41) : AC(17)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

Topically applied nanoparticle zinc oxide from sunscreen are capable of being absorbed through the human skin.

Click here to read the entire abstract

Pubmed Data : Toxicol Sci. 2010 Nov;118(1):140-9. Epub 2010 Aug 12. PMID: 20705894

Article Published Date : Nov 01, 2010

Study Type : Human Study

Additional Links

Diseases : Chemical Exposure : CK(49) : AC(15)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Sunscreen : CK(71) : AC(14), Zinc Oxide : CK(18) : AC(8)

Adverse Pharmacological Actions : Bioaccumulator : CK(104) : AC(23)

"Metal and silicate particles including nanoparticles are present in electronic cigarette cartomizer fluid and aerosol."

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2013 ;8(3):e57987. Epub 2013 Mar 20. PMID: 23526962

Article Published Date : Dec 31, 2012

Study Type : Environmental, In Vitro Study, Review

Additional Links

Diseases : Lung Inflammation : CK(339) : AC(4)

Additional Keywords : metalloestrogens

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Electronic Cigarettes : CK(2) : AC(1), Ethylene Glycol : CK(2) : AC(1), Nanoparticles : CK(24) : AC(13), Tin : CK(4) : AC(3)

Adverse Pharmacological Actions : Endocrine Disruptor : CK(478) : AC(81)

"Neurotoxicity of engineered nanoparticles from metals."

Click here to read the entire abstract

Pubmed Data : CNS Neurol Disord Drug Targets. 2012 Feb ;11(1):65-80. PMID: 22229317

Article Published Date : Jan 31, 2012

Study Type : Animal Study

Additional Links

Diseases : Neurotoxicity : CK(37) : AC(15)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Nanoparticles : CK(24) : AC(13)

Adverse Pharmacological Actions : Neurotoxic : CK(1076) : AC(179)

Food chain transport of nanoparticles affects behaviour and fat metabolism in fish.

Click here to read the entire abstract

Pubmed Data : PLoS One. 2012 ;7(2):e32254. Epub 2012 Feb 22. PMID: 22384193

Article Published Date : Jan 01, 2012

Study Type : Animal Study

Additional Links

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Nanoparticles derived from metals are capable of inducing brain dysfunction.

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Pubmed Data : Prog Brain Res. 2007;162:245-73. PMID: 17645923

Article Published Date : Jan 01, 2007

Study Type : Animal Study

Additional Links

Diseases : Brain Inflammation : CK(79) : AC(35)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Nanoparticles : CK(24) : AC(13)

Nanoparticles may have potential neurotoxicity.

Click here to read the entire abstract

Pubmed Data : J Reprod Med. 2002 Oct;47(10):821-4. PMID: 20433914

Article Published Date : Oct 01, 2002

Study Type : Animal Study

Additional Links

Diseases : Neurodegenerative Diseases : CK(1743) : AC(420)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Oral exposure to polystyrene nanoparticles affects iron absorption and caused remodelling of the intestinal villi in chickens.

Click here to read the entire abstract

Pubmed Data : Nat Nanotechnol. 2012 ;7(4):264-71. Epub 2012 Feb 12. PMID: 22327877

Article Published Date : Jan 01, 2012

Study Type : Animal Study

Additional Links

Diseases : Anemia: Iron Deficiency : CK(85) : AC(11), Iron Deficiency/Malabsorption : CK(2) : AC(1), Malabsorption Syndrome : CK(34) : AC(11), Microvilli atrophy : CK(4) : AC(1)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Polystyrene nanoparticles : CK(16) : AC(2)

Polystyrene nanoparticle uptake by the rat gastrointestinal mucosa results in their systemic bodily distribution.

Click here to read the entire abstract

Pubmed Data : J Pharm Pharmacol. 1990 Dec ;42(12):821-6. PMID: 1983142

Article Published Date : Dec 01, 1990

Study Type : Animal Study

Additional Links

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Polystyrene nanoparticles : CK(16) : AC(2)

Polystyrene nanoparticles are capable of entering through the blood-brain-barrier in an animal model of brain ischemia and perfusion.

Click here to read the entire abstract

Pubmed Data : Anal Chem. 2004 Aug 1 ;76(15):4465-71. PMID: 15283589

Article Published Date : Aug 01, 2004

Study Type : Animal Study

Additional Links

Diseases : Blood-Brain-Barrier Disorders : CK(25) : AC(15)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Polystyrene nanoparticles : CK(16) : AC(2)

The implementation of nanotechnology may result in significant genotoxicity.

Click here to read the entire abstract

Pubmed Data : Nano Lett. 2007 Dec;7(12):3592-7. Epub 2007 Nov 29. PMID: 18044946

Article Published Date : Dec 01, 2007

Study Type : Animal Study

Additional Links

Diseases : DNA damage : CK(711) : AC(293), Embryopathies : CK(2) : AC(1)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Titanium dioxide nanoparticles cause acute toxicity, thrombosis, liver, lung and kidney damage when injected into mice.

Click here to read the entire abstract

Pubmed Data : J Appl Toxicol. 2009 May;29(4):330-7. PMID: 19156710

Article Published Date : May 01, 2009

Study Type : Animal Study

Additional Links

Diseases : Kidney Damage : CK(120) : AC(42), Lung Damage : CK(8) : AC(4)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Titanium Dioxide : CK(41) : AC(17)

Adverse Pharmacological Actions : Cytotoxic : CK(73) : AC(35)

Titanium dioxide nanoparticles contribute to pulmonary inflammation after intraperitoneal administration in lungs of mice.

Click here to read the entire abstract

Pubmed Data : J Toxicol Environ Health A. 2010 Jan;73(5):396-409. PMID: 20155581

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Diseases : Lung Injury: Acute : CK(32) : AC(11)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Titanium Dioxide : CK(41) : AC(17)

Adverse Pharmacological Actions : Inflammatory : CK(150) : AC(37)

"Engineering Nano- and Microparticles to Tune Immunity."

Click here to read the entire abstract

Pubmed Data : Adv Mater. 2012 May 29. Epub 2012 May 29. PMID: 22641380

Article Published Date : May 29, 2012

Study Type : Review

Additional Links

Additional Keywords : Mad Science : CK(61) : AC(24), Natural vs. Synthetic Immunity

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Amino-functionalized polystyrene nanoparticles activate the NLRP3 inflammasome in human macrophages.

Click here to read the entire abstract

Pubmed Data : ACS Nano. 2011 Dec 27 ;5(12):9648-57. Epub 2011 Dec 8. PMID: 22111911

Article Published Date : Dec 27, 2011

Study Type : In Vitro Study

Additional Links

Diseases : Inflammation : CK(1077) : AC(363)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Polystyrene nanoparticles : CK(16) : AC(2)

Adverse Pharmacological Actions : Immunoreactive : CK(127) : AC(17), Inflammatory : CK(150) : AC(37)

Biofuel cell as a power source for electronic contact lenses.

Click here to read the entire abstract

Pubmed Data : Biosens Bioelectron. 2012 Aug ;37(1):38-45. Epub 2012 May 4. PMID: 22621980

Article Published Date : Jul 31, 2012

Study Type : Review

Additional Links

Additional Keywords : Mad Science : CK(61) : AC(24), Transhumanism : CK(3) : AC(3)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Design of synthetic polymer nanoparticles that capture and neutralize a toxic peptide.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Small. 2009 Jul ;5(13):1562-8. PMID: 19296557

Article Published Date : Jul 01, 2009

Study Type : Review

Additional Links

Additional Keywords : Mad Science : CK(61) : AC(24), Plastic Antibodies : CK(5) : AC(4), Transhumanism : CK(3) : AC(3)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Nanoparticle sunscreens may have photocarcinogenic potential.

Click here to read the entire abstract

Pubmed Data : Australas J Dermatol. 2011 Feb;52(1):1-6. Epub 2010 Aug 16. PMID: 21332685

Article Published Date : Feb 01, 2011

Study Type : Review

Additional Links

Diseases : Skin Cancer : CK(417) : AC(171)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Nanoparticles : CK(24) : AC(13), Sunscreen : CK(71) : AC(14), Titanium Dioxide : CK(41) : AC(17)

Adverse Pharmacological Actions : Carcinogenic : CK(912) : AC(117)

Nanoparticle zinc oxide and titanium dioxide exhibit genotoxicity and cytotoxicity.

Click here to read the entire abstract

Pubmed Data : Nanomedicine (Lond). 2010 Oct;5(8):1193-203. PMID: 21039197

Article Published Date : Oct 01, 2010

Study Type : In Vitro Study

Additional Links

Diseases : DNA damage : CK(711) : AC(293)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Titanium Dioxide : CK(41) : AC(17), Zinc Oxide : CK(18) : AC(8)

Adverse Pharmacological Actions : Genotoxic : CK(146) : AC(61)

Nanoparticles exhibit size dependent neurotoxicity.

Click here to read the entire abstract

Pubmed Data : Arch Toxicol. 2011 Dec ;85(12):1575-88. Epub 2011 Sep 1. PMID: 21881955

Article Published Date : Dec 01, 2011

Study Type : In Vitro Study

Additional Links

Diseases : DNA damage : CK(711) : AC(293)

Pharmacological Actions : Tumor Suppressor Protein p53 Upregulation : CK(146) : AC(105)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Polystyrene nanoparticles : CK(16) : AC(2)

Adverse Pharmacological Actions : Genotoxic : CK(146) : AC(61)

Polymeric (polystyrene) nano particles have hemolytic properties.

Click here to read the entire abstract

Pubmed Data : IEEE Trans Nanobioscience. 2011 Dec ;10(4):259-61. Epub 2011 Nov 22. PMID: 22128012

Article Published Date : Dec 01, 2011

Study Type : In Vitro Study

Additional Links

Diseases : Anemia: Hemolytic : CK(76) : AC(8), Blood Diseases : CK(30) : AC(2)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Polystyrene nanoparticles : CK(16) : AC(2)

Adverse Pharmacological Actions : Hemolytic : CK(17) : AC(4)

Polystyrene nanoparticles absorption within cells can be inhibited with genistein

Click here to read the entire abstract

Pubmed Data : PLoS One. 2011 ;6(9):e24438. Epub 2011 Sep 19. PMID: 21949717

Article Published Date : Jan 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Genistein : CK(450) : AC(174)

Diseases : Nanoparticle Toxicity: Polystyrene : CK(1) : AC(1)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Polystyrene nanoparticles : CK(16) : AC(2)

Polystyrene nanoparticles affects blood coagulation.

Click here to read the entire abstract

Pubmed Data : Nanomedicine. 2011 Dec 23. Epub 2011 Dec 23. PMID: 22197724

Article Published Date : Dec 23, 2011

Study Type : In Vitro Study

Additional Links

Diseases : Blood Coagulation Disorders : CK(42) : AC(8)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Polystyrene nanoparticles : CK(16) : AC(2)

Review: factors affecting the oral uptake and translocation of polystyrene nanoparticles

Click here to read the entire abstract

Pubmed Data : J Drug Target. 1995 ;3(1):65-70. PMID: 7655823

Article Published Date : Jan 01, 1995

Study Type : Review

Additional Links

Additional Keywords : Lectins : CK(58) : AC(36)

Anti Therapeutic Actions : Nanotechnology : CK(67) : AC(28)

Problem Substances : Polystyrene nanoparticles : CK(16) : AC(2)

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