Vaccination: Diphtheria-Pertussis-Tetanus

Vaccination: Diphtheria-Pertussis-Tetanus

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View the Evidence: Problematic Actions

DTP or tetanus vaccination increases the risk of allergies and related respiratory symptoms in children and adolescents.

Pubmed Data : J Manipulative Physiol Ther. 2000 Feb;23(2):81-90. PMID: 10714532
Article Published Date : Feb 01, 2000
Study Type : Meta Analysis
Additional Links
Diseases : Allergies : CK(520) : AC(96), Allergies: Childhood : CK(70) : AC(5), Asthma : CK(991) : AC(140), Hypersensitivity : CK(64) : AC(15), Vaccine-induced Toxicity : CK(1242) : AC(180)
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31), Vaccination: Tetanus : CK(61) : AC(8)

Vaccination in infants less than 3 months is associated with an increased risk of sudden infant death syndrome.

Pubmed Data : Fundam Clin Pharmacol. 1995;9(3):263-70. PMID: 7557822
Article Published Date : Jan 01, 1995
Study Type : Meta Analysis
Additional Links
Diseases : Sudden Infant Death Syndrome (SIDS) : CK(138) : AC(18), Vaccine-induced Toxicity : CK(1242) : AC(180)
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31), Vaccination: Polio : CK(94) : AC(15)

Vaccination is associated with a rare autoimmune neurological condition transverse myelitis.

Pubmed Data : Lupus. 2009 Nov;18(13):1198-204. PMID: 19880568
Article Published Date : Nov 01, 2009
Study Type : Meta Analysis
Additional Links
Diseases : Myelitis : CK(39) : AC(5), Vaccine-induced Toxicity : CK(1242) : AC(180)
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31), Vaccination: Hepatitis B : CK(367) : AC(50), Vaccination: Mumps-Measles-Rubella (MMR) : CK(228) : AC(26)

Vaccination is associated with an increased risk for hemolytic anemia.

Pubmed Data : Vaccine. 2009 Dec 9;27(52):7394-7. Epub 2009 Sep 18. PMID: 19766577
Article Published Date : Dec 09, 2009
Study Type : Meta Analysis
Additional Links
Diseases : Hemolytic Anemia : CK(75) : AC(5), Vaccine-induced Toxicity : CK(1242) : AC(180)
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31), Vaccination: Hepatitis B : CK(367) : AC(50)

Acute necrotizing encephalopathy secondary to diphtheria, tetanus toxoid and whole-cell pertussis vaccination has been reported.

Pubmed Data : Pediatr Radiol. 2010 Jul;40(7):1281-4. Epub 2010 Jan 30. PMID: 20119724
Article Published Date : Jul 01, 2010
Study Type : Human Study
Additional Links
Diseases : Encephalopathy: Acute Necrotizing : CK(20) : AC(2), Vaccine-induced Toxicity : CK(1242) : AC(180)
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31)

Adverse effects of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine in 6- to 7-year-old children.

Pubmed Data : Pediatr Neonatol. 2011 Feb;52(1):38-41. Epub 2011 Feb 17. PMID: 21385656
Article Published Date : Feb 01, 2011
Study Type : Human Study
Additional Links
Diseases : Tetanus : CK(47) : AC(5), Vaccine-induced Toxicity : CK(1242) : AC(180)
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31)

Among female infants, those who receive both BCG and DTP vaccines experience higher mortality than those who receive only one of the two vaccines.

Pubmed Data : Trop Med Int Health. 2005 Oct;10(10):947-55. PMID: 16185228
Article Published Date : Oct 01, 2005
Study Type : Human Study
Additional Links
Diseases : Infant Mortality : CK(249) : AC(25), Vaccine-induced Toxicity : CK(1242) : AC(180)
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: BCG (Tuberculosis) : CK(33) : AC(4), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31)

Breastfeeding attenuates reductions in energy intake induced by a mild immunologic stimulus represented by DPTH immunization.

Pubmed Data : J Nutr. 2002 Jun;132(6):1293-8. PMID: 12042449
Article Published Date : Jun 01, 2002
Study Type : Human Study
Additional Links
Substances : Breast Milk : CK(428) : AC(49)
Diseases : Vaccine-induced Toxicity : CK(1242) : AC(180)
Therapeutic Actions : Breastfeeding : CK(739) : AC(77)
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(1224) : AC(444)
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31)

Delay in diphtheria, pertussis, tetanus vaccination is associated with a reduced risk of childhood asthma.

Pubmed Data : J Allergy Clin Immunol. 2008 Mar ;121(3):626-31. Epub 2008 Jan 18. PMID: 18207561
Article Published Date : Feb 29, 2008
Study Type : Human Study
Additional Links
Diseases : Asthma : CK(991) : AC(140)
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31)

Despite the CDC's current recommendation to vaccinate postpartum women before hospital discharge with the tetanus and diphtheria toxoids and acellular pertussis (Tdap) vaccine in order to prevent pertussis infection in their offspring, it does not reduce

Pubmed Data : Clin Infect Dis. 2011 Nov 10. Epub 2011 Nov 10. PMID: 22075790
Article Published Date : Nov 10, 2011
Study Type : Human Study
Additional Links
Diseases : Pertussis : CK(142) : AC(14), Whooping Cough : CK(129) : AC(7)
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31), Vaccination: Pertussis : CK(140) : AC(20), Vaccination: Tetanus : CK(61) : AC(8)

Diphtheria-tetanus-pertussis vaccine administered simultaneously with measles vaccine is associated with increased morbidity and poor growth in girls.

Pubmed Data : Vaccine. 2011 Jan 10;29(3):487-500. Epub 2010 Nov 18. PMID: 21093496
Article Published Date : Jan 10, 2011
Study Type : Human Study
Additional Links
Diseases : Vaccine-induced Toxicity : CK(1242) : AC(180)
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: Combinations : CK(20) : AC(2), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31), Vaccination: Measles : CK(157) : AC(16)

DPT vaccines have been associated with recurrent seizures.

Pubmed Data : Am J Dis Child. 1984 Oct;138(10):908-11. PMID: 6206715
Article Published Date : Oct 01, 1984
Study Type : Human Study
Additional Links
Diseases : Pertussis : CK(142) : AC(14), Seizures : CK(135) : AC(33), Vaccine-induced Toxicity : CK(1242) : AC(180)
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31)

Hair mercury in breast-fed infants exposed to thimerosal-preserved vaccines indicates significant levels of exposure.

Pubmed Data : Eur J Pediatr. 2007 Sep;166(9):935-41. Epub 2007 Jan 20. PMID: 17237965
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Diseases : Mercury Poisoning : CK(172) : AC(45), Vaccine-induced Toxicity : CK(1242) : AC(180)
Therapeutic Actions : Breastfeeding : CK(739) : AC(77)
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31), Vaccination: Hepatitis B : CK(367) : AC(50)

Incidence of adverse reactions to vaccines in pediatric populations are under-reported and may be as high as 43.4% for certain vaccine combinations.

Pubmed Data : Clin Drug Investig. 2004;24(8):457-63. PMID: 17523706
Article Published Date : Jan 01, 2004
Study Type : Human Study
Additional Links
Diseases : Vaccine-induced Toxicity : CK(1242) : AC(180)
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31), Vaccination: Mumps-Measles-Rubella (MMR) : CK(228) : AC(26)

Pertussis epidemic despite high levels of vaccination coverage with acellular pertussis vaccine.

Article Published Date : Nov 07, 2013
Study Type : Human Study
Additional Links
Diseases : Pertussis : CK(142) : AC(14), Whooping Cough : CK(129) : AC(7)
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31)

Since the 1993 pertussis epidemic in Cincinnati occurred primarily among children who had been appropriately immunized, it is clear that the whole-cell pertussis vaccine failed to give full protection against the disease.

Pubmed Data : N Engl J Med. 1994 Jul 7;331(1):16-21. PMID: 8202096
Article Published Date : Jul 07, 1994
Study Type : Human Study
Additional Links
Diseases : Pertussis : CK(142) : AC(14), Whooping Cough : CK(129) : AC(7)
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31), Vaccination: Pertussis : CK(140) : AC(20)

Sudden infant death syndrome and DTP vaccine timing may be linked.

Pubmed Data : Otol Neurotol. 2002 Jul;23(4):447-51. PMID: 6835859
Article Published Date : Jul 01, 2002
Study Type : Human Study
Additional Links
Diseases : Sudden Infant Death Syndrome (SIDS) : CK(138) : AC(18)
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31)

Sudden Infant Death syndrome mortality rate in the period zero to three days following DTP was found to be 7.3 times higher than in the period 30 days after immunization.

Pubmed Data : Am J Public Health. 1987 Aug;77(8):945-51. PMID: 3496805
Article Published Date : Aug 01, 1987
Study Type : Human Study
Additional Links
Diseases : Sudden Infant Death Syndrome (SIDS) : CK(138) : AC(18), Vaccine-induced Toxicity : CK(1242) : AC(180)
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31)

The association with DTwP vaccines and increased infant mortality in females may be due to vaccine adjuvants and Th2 polarizing effects.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Trop Med. 2011 ;2011:706304. Epub 2011 May 5. PMID: 21760811
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Diseases : Immune Dysregulation: TH1/TH2 imbalance : CK(148) : AC(37), Infant Mortality : CK(249) : AC(25), Vaccine-induced Toxicity : CK(1242) : AC(180)
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31), Vaccination: Pertussis : CK(140) : AC(20), Vaccination: Tetanus : CK(61) : AC(8), Vaccinaton: Diptheria : CK(50) : AC(2)
Problem Substances : Adjuvant : CK(18) : AC(6), Aluminum Hydroxide : CK(67) : AC(14), Vaccine Adjuvants : CK(403) : AC(79)

The combination of MMR and DTaP-Hib-IPV vaccination is associated with significantly increased rates of adverse effects.

Pubmed Data : J Radiol Prot. 2009 Sep;29(3):429-43. Epub 2009 Aug 18. PMID: 20166340
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: Combinations : CK(20) : AC(2), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31), Vaccination: Haemophilus Influenzae : CK(25) : AC(4), Vaccination: Mumps-Measles-Rubella (MMR) : CK(228) : AC(26), Vaccination: Polio : CK(94) : AC(15)

The use of misoprostol for early pregnancy failure after failed expectant management is less costly than curettage.

Pubmed Data : Hum Reprod. 2005 Apr;20(4):1067-71. Epub 2004 Dec 23. PMID: 15618248
Article Published Date : Apr 01, 2005
Study Type : Human Study
Additional Links
Diseases : Miscarriage : CK(313) : AC(36), Miscarriage: Medical Intervention : CK(125) : AC(14)
Additional Keywords : Surgical Alternatives : CK(20) : AC(2)
Anti Therapeutic Actions : Obstetric Interventions : CK(1030) : AC(69), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31)

This study demonstrated the differences between natural B. pertussis immune response and vaccine induced immune response.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Immunol. 2015 ;16:40. Epub 2015 Jul 1. PMID: 26129684
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Whooping Cough : CK(129) : AC(7)
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31), Vaccination: Pertussis : CK(140) : AC(20)

Thrombocytopenic purpura following vaccination in early childhood has been reported.

Pubmed Data : J Chin Med Assoc. 2010 Dec;73(12):634-7. PMID: 21145511
Article Published Date : Dec 01, 2010
Study Type : Human Study
Additional Links
Diseases : Purpura: Thrombocytopenic : CK(231) : AC(25), Vaccine-induced Toxicity : CK(1242) : AC(180)
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31), Vaccination: Hepatitis B : CK(367) : AC(50), Vaccination: Mumps-Measles-Rubella (MMR) : CK(228) : AC(26)

Timing of routine immunisations (earlier = increased) and subsequent hay fever risk.

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Dis Child. 2005 Jun ;90(6):567-73. PMID: 15908618
Article Published Date : May 31, 2005
Study Type : Human Study
Additional Links
Diseases : Allergic Rhinitis : CK(340) : AC(40), Immune Dysregulation: TH1/TH2 imbalance : CK(148) : AC(37), Vaccine-induced Toxicity : CK(1242) : AC(180)
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31)

Vaccination timing and co-administration may be associated with increased mortality, especially in females.

Pubmed Data : Vaccine. 2006 May 29;24(22):4701-8. Epub 2006 Mar 31. PMID: 16621182
Article Published Date : May 29, 2006
Study Type : Human Study
Additional Links
Anti Therapeutic Actions : Vaccination: All : CK(4729) : AC(366), Vaccination: BCG (Tuberculosis) : CK(33) : AC(4), Vaccination: Diphtheria-Pertussis-Tetanus : CK(314) : AC(31), Vaccination: Mumps-Measles-Rubella (MMR) : CK(228) : AC(26)

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