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Depression: 21st Century Solutions + The Dark Side of Wheat

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Abstract Title:

Acemannan hydrogel dressing versus saline dressing for pressure ulcers. A randomized, controlled trial.

Abstract Source:

Adv Wound Care. 1998 Oct ;11(6):273-6. PMID: 10326343

Abstract Author(s):

D R Thomas, P S Goode, K LaMaster, T Tennyson

Article Affiliation:

D R Thomas

Abstract:

Aloe vera has been used for centuries as a topical treatment for various conditions and as a cathartic. An amorphous hydrogel dressing derived from the aloe plant (Carrasyn Gel Wound Dressing, Carrington Laboratories, Inc., Irving, TX) is approved by the Food and Drug Administration for the management of Stages I through IV pressure ulcers. To evaluate effectiveness of this treatment, 30 patients were randomized to receive either daily topical application of the hydrogel study dressing (acemannan hydrogel wound dressing) or a moist saline gauze dressing. Complete healing of the study ulcer occurred in 19 of 30 subjects (63%) during the 10-week observation period. No difference was observed in complete healing between the experimental and the control groups (odds ratio 0.93, 95% CI 0.16, 5.2). This study indicates that the acemannan hydrogel dressing is as effective as, but is not superior to, a moist saline gauze wound dressing for the management of pressure ulcers.

Study Type : Human Study

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Sayer Ji
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Depression: 21st Century Solutions + The Dark Side of Wheat

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