Allopurinol-induced hypersensitivity syndrome resulting in death has been reported. - GreenMedInfo Summary

Abstract Title:

[Allopurinol-induced hypersensitivity syndrome resulting in death].

Abstract Source:

Med Klin (Munich). 2010 Apr;105(4):262-6. PMID: 20455046

Abstract Author(s):

Sören Laurisch, Maren Jaedtke, Reyhan Demir, Sajoscha A Sorrentino, Jan T Kielstein, Hans-Oliver Rennekampff, Peter M Vogt, Gerd P Meyer, Martin Fuchs, Gunnar Klein, Hartmut Drexler, Bernhard Schieffer, L Christian Napp

Article Affiliation:

Klinik für Kardiologie und Angiologie, Medizinische Hochschule Hannover, Hannover, Germany. Laurisch.Soeren@mh-hannover.de

Abstract:

The present report describes the case of a 67-year-old patient who developed an allopurinol-induced hypersensitivity syndrome (AHS) with toxic epidermal necrolysis and subsequently died of septic multiorgan failure. Considering the increasing prescription rate of allopurinol, the present case report intends to demonstrate the underestimated threat of AHS.

Article Published Date : Apr 01, 2010
Study Type : Human Study
Additional Links
Diseases : Drug-Induced Toxicity : CK(560) : AC(78)
Problem Substances : Allopurinol : CK(37) : AC(5)

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