Allopurinol-induced hypersensitivity syndrome resulting in death has been reported. - GreenMedInfo Summary
[Allopurinol-induced hypersensitivity syndrome resulting in death].
Med Klin (Munich). 2010 Apr;105(4):262-6. PMID: 20455046
Klinik für Kardiologie und Angiologie, Medizinische Hochschule Hannover, Hannover, Germany. Laurisch.Soeren@mh-hannover.de
The present report describes the case of a 67-year-old patient who developed an allopurinol-induced hypersensitivity syndrome (AHS) with toxic epidermal necrolysis and subsequently died of septic multiorgan failure. Considering the increasing prescription rate of allopurinol, the present case report intends to demonstrate the underestimated threat of AHS.