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Abstract Title:

American ginseng berry juice intake reduces blood glucose and body weight in ob/ob mice.

Abstract Source:

J Food Sci. 2007 Oct;72(8):S590-4. PMID: 17995625

Abstract Author(s):

J T Xie, C Z Wang, M Ni, J A Wu, S R Mehendale, H H Aung, A Foo, C S Yuan

Abstract:

Diabetes is a serious chronic metabolic disease and has a significant impact on patients' lives and the health care system. We previously observed that the organic solvent extract of American ginseng berry possessed significant antidiabetic effects in obese diabetic ob/ob mice after intraperitoneal injection. If American ginseng berry is useful as a dietary supplement, simple preparation and oral intake would be a convenient, safe, and practical means for consumers. In this study, the simply prepared berry juice was first analyzed using high-performance liquid chromatography, and then administered orally in the ob/ob mice. The animals received daily berry juice 0.6 mL/kg or vehicle for 10 consecutive days. The results indicated that oral juice administration significantly lowered fasting blood glucose levels, and this effect continued for at least 10 d after cessation of the treatment. Data from intraperitoneal glucose tolerance test demonstrated that there was a notable improvement in glucose tolerance in the juice treated group. In addition, the berry juice significantly reduced body weight. Our data suggest that ginseng berry juice, as a dietary supplement, may have functional efficacy in consumers with diabetes.

Study Type : Animal Study

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Sayer Ji
Founder of GreenMedInfo.com

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