Abstract Title:

Analysis of Bisphenol A, Nonylphenol and Natural Estrogens in Vegetables and Fruits Using Gas Chromatography-Tandem Mass Spectrometry.

Abstract Source:

J Agric Food Chem. 2012 Dec 6. Epub 2012 Dec 6. PMID: 23215552

Abstract Author(s):

Jian Lu, Jun Wu, Peter J Stoffella, Patrick Wilson

Abstract:

Bisphenol A (BPA), nonylphenol (NP), and steroidal estrogens in vegetables and fruits were analyzed using gas chromatography with tandem mass spectrometry (GC-MS/MS). Isotope dilution standards were spiked before the extraction to account for extraction inefficiency and loss of analytes during sample workup. Recoveries were greater than 90% for all of the compounds in each matrix. The limit of detection (LOD) ranged from 0.03 to 0.3µg kg-1 while the limit of quantitation (LOQ) ranged from 0.1 to 1.0 µg kg-1. All analytes can be monitored in a single GC-MS/MS run with a run time of 20 min. Occurrence of these endocrine-disrupting chemicals (EDCs) in vegetables and fruits from local markets was observed using the established analytical method. BPA was detected in all vegetable and fruit samples, ranging from 0.2±0.1 to 9.0±4.9 µg kg-1, indicating significant exposure potential for humans. NP was detected in pumpkin, sweet potato, citrus, and apple samples. The concentration of 4-n-NP ranged from 5.3±2.4 to 18.9±8.0µg kg-1 while that of the 4-NP ranged from 5.1±2.6 to 12.2±3.6 µg kg-1. Concentrations of 17-β-estradiol in vegetables and fruits ranged from 1.3±0.4 to 2.2±1.0 µg kg-1 except those in tomato and strawberry. The estimated daily intake of 17-β-estradiol was beyond the recommended acceptabledaily intake (ADI) for children as recommended by the Joint FAO/WHO Expert Committee on Food Additives (JECFA).

Study Type : Plant Study
Additional Links
Adverse Pharmacological Actions : Bioaccumulator : CK(107) : AC(26)

Print Options


Disqus

Login to Comment

Commenting is limited to Members only. If you are already a member, please login to post a comment. If you do not have a member account and would like to become a member, please click here to begin the process to become a member.

Key Research Topics

Popular Threads

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2016 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.