Bay leaf contains compounds with significant peroxynitrate-induced tyrosine nitration. - GreenMedInfo Summary
Essential oils of commonly used plants as inhibitors of peroxynitrite-induced tyrosine nitration.
Fitoterapia. 2005 Jul;76(5):481-3. PMID: 15967593
Dipartimento di Chimica Bioorganica e Biofarmacia, Università di Pisa, via Bonanno 33, 56126 Pisa, Italy. [email protected]
The essential oils obtained from fifteen relevant and commonly used plants belonging to Cruciferae, Lamiaceae, Lauraceae, Apiaceae, and Zingiberaceae were screened using an in vitro model of peroxynitrite-induced tyrosine nitration. Almost complete inhibition of 3-nitrotyrosine formation (91% at 300 microg/ml) was achieved only with the essential oil obtained from the leaves of Laurus nobilis. 1,8-Cineol, accounting for a 50% of this essential oil, which resulted as inactive in this model, thus evidencing a major role for the minor volatile compounds present in the leaves.