Article Publish Status: FREE
Abstract Title:

Kaempferia parviflora extract increases whole-body energy expenditure in humans: roles of brown adipose tissue.

Abstract Source:

J Nutr Sci Vitaminol (Tokyo). 2015 ;61(1):79-83. PMID: 25994142

Abstract Author(s):

Mami Matsushita, Takeshi Yoneshiro, Sayuri Aita, Tomoyasu Kamiya, Nobutaka Kusaba, Kazuya Yamaguchi, Kinya Takagaki, Toshimitsu Kameya, Hiroki Sugie, Masayuki Saito

Article Affiliation:

Mami Matsushita

Abstract:

Kaempferia parviflora extract (KP) has been reported to have a preventive effect on obesity in mice, probably by increasing energy expenditure (EE). The aims of the current study were to examine the acute effects of KP ingestion on whole-body EE in humans and to analyze its relation to the activity of brown adipose tissue (BAT), a site of non-shivering thermogenesis. After an oral ingestion of an ethanol extract of KP, EE increased significantly, showing a maximal increase of 229±69 kJ/d at 60 min, while it did not change after placebo ingestion. To evaluate BAT activity, the subjects underwent fluorodeoxyglucose-positron emission tomography, and divided into two groups with high- and low-BAT activities. A similar and greater response of EE to KP ingestion was observed inthe high-BAT group (351±50 kJ/d at 60 min), but not in the low activity group. Placebo ingestion did not cause any significant EE change in either group. These results indicate that a single oral ingestion of the KP extract can potentially increase whole-body EE probably through the activation of BAT in healthy men, and may be useful as an anti-obesity regimen.

Study Type : Human Study

Print Options


Key Research Topics

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2024 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.