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Depression: 21st Century Solutions + The Dark Side of Wheat

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Abstract Title:

The main beneficial effect of roselle (Hibiscus sabdariffa) on obesity is not only related to its anthocyanin content.

Abstract Source:

J Sci Food Agric. 2018 Jun 26. Epub 2018 Jun 26. PMID: 29943479

Abstract Author(s):

Elizabeth Morales-Luna, Iza F Pérez-Ramírez, Luis M Salgado, Eduardo Castaño-Tostado, Carlos A Gómez-Aldapa, Rosalía Reynoso-Camacho

Article Affiliation:

Elizabeth Morales-Luna

Abstract:

BACKGROUND: The calyxes of roselle (Hibiscus sabdariffa) are recognized for their high nutraceutical value because they decrease body weight and obesity complications. These effects have been attributed mainly to anthocyanins. However, the calyxes comprise important concentration of flavonoids, phenolic, and organic acids, which could also contribute to these effects. The objective of this work was to determine the effect of the Alma Blanca white roselle variety on obesity and hepatic steatosis in high-fat, high-fructose, diet-fed rats and compare its beneficial effects with the red variety (Criolla), which has been more extensively studied.

RESULTS: Aqueous and methanolic extracts were prepared from two roselle varieties, Alma Blanca (white) and Criolla (red). The phytochemical profiles were determined using high-performance liquid chromatography-mass spectrometry (HPLC-MS). Criolla extracts contain principally anthocyanins, phenolic acids, and flavonoids. Anthocyanins were not detected in Alma Blanca. The aqueous extracts of both varieties prevented body-weight gain and decreased adipocytes hyperplasia on rats fed a hypercaloric diet. These extracts also protected against hepatic steatosis. These benefits were associated with hibiscus, dimethyl hibiscus, and hydroxycitric acid.

CONCLUSION: These results demonstrated that calyxes from Hibiscus sabdariffa contain compounds that are different from anthocyanins, with potential benefits to health. The organic acids were strongly associated with these beneficial health effects.© 2018 Society of Chemical Industry.

Study Type : Animal Study

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Sayer Ji
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Depression: 21st Century Solutions + The Dark Side of Wheat

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