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Depression: 21st Century Solutions + The Dark Side of Wheat

Abstract Title:

Blood pressure lowering, fibrinolysis enhancing and antioxidant activities of cardamom (Elettaria cardamomum).

Abstract Source:

Indian J Biochem Biophys. 2009 Dec;46(6):503-6. PMID: 20361714

Abstract Author(s):

S K Verma, Vartika Jain, S S Katewa

Article Affiliation:

Indigenous Drug Research Center, Department of Medicine, RNT Medical College, Udaipur 313 001, Rajasthan, India. skvermaster@gmail.com

Abstract:

Elettaria cardamomum (L.) Maton. (Small cardamom) fruit powder was evaluated for its antihypertensive potential and its effect on some of the cardiovascular risk factors in individuals with stage 1 hypertension. Twenty, newly diagnosed individuals with primary hypertension of stage 1 were administered 3 g of cardamom powder in two divided doses for 12 weeks. Blood pressure was recorded initially and at 4 weeks interval for 3 months. Blood samples were also collected initially and at 4 weeks interval for estimation of lipid profile, fibrinogen and fibrinolysis. Total antioxidant status, however, was assessed initially and at the end of the study. Administration of 3 g cardamom powder significantly (p<0.001) decreased systolic, diastolic and mean blood pressure and significantly (p<0.05) increased fibrinolytic activity at the end of 12th week. Total antioxidant status was also significantly (p<0.05) increased by 90% at the end of 3 months. However, fibrinogen and lipid levels were not significantly altered. All study subjects experienced a feeling of well being without any side-effects. Thus, the present study demonstrates that small cardamom effectively reduces blood pressure, enhances fibrinolysis and improves antioxidant status, without significantly altering blood lipids and fibrinogen levels in stage 1 hypertensive individuals.

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Sayer Ji
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Depression: 21st Century Solutions + The Dark Side of Wheat

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