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Depression: 21st Century Solutions + The Dark Side of Wheat

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Abstract Title:

Chemical constituents from Curcuma longa L. and their inhibitory effects of nitric oxide production.

Abstract Source:

Nat Prod Res. 2017 Jul 20:1-6. Epub 2017 Jul 20. PMID: 28726500

Abstract Author(s):

Ting Yuan, Cuiyun Zhang, Chongyue Qiu, Guiyang Xia, Fei Wang, Bin Lin, Hua Li, Lixia Chen

Article Affiliation:

Ting Yuan

Abstract:

A new bisabolane-type sesquiterpenoid, turmerone Q (1), along with six known compounds (2-7), were isolated from the rhizomes of Curcuma longa L. The structural elucidation of the new compound was conducted using (1)H NMR, (13)C NMR, HSQC, HMBC and NOESY spectroscopic analyses. The absolute configuration of 1 was elucidated by comparison of the experimental and calculated ECD spectra. The anti-inflammatory effects of 1-7 were evaluated through lipopolysaccharide-induced nitric oxide (NO) production in RAW 264.7 macrophages assays, and compounds 6 and 7 showed potent inhibitory activity against NO production.

Study Type : In Vitro Study

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Sayer Ji
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Depression: 21st Century Solutions + The Dark Side of Wheat

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