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Abstract Title:

Cranberry juice for the prevention of recurrent urinary tract infections: a randomized controlled trial in children.

Abstract Source:

Scand J Urol Nephrol. 2009;43(5):369-72. PMID: 19921981

Abstract Author(s):

Pietro Ferrara, Luciana Romaniello, Ottavio Vitelli, Antonio Gatto, Martina Serva, Luigi Cataldi

Article Affiliation:

Department of Pediatrics, Catholic University, A. Gemelli Hospital, Rome, Italy. pferrara@rm.unicatt.it

Abstract:

OBJECTIVE: This study compares the effects of daily cranberry juice to those of Lactobacillus in children with recurrent urinary tract infections (UTIs).

MATERIAL AND METHODS: Eighty-four girls aged between 3 and 14 years were randomized to cranberry, Lactobacillus or control in three treatment arms: G1, cranberry juice 50 ml daily (n=28); G2, 100 ml of Lactobacillus GG drink on 5 days a month (n=27); and G3, controls (n=29). The study lasted for 6 months.

RESULTS: Only four subjects withdrew: 1/28 (3.5%) from G1, 1/27 (3.7%) from G2 and 2/29 (6.8%) from G3, because of poor compliance to the established protocol. There were 34 episodes of UTIs in this cohort: 5/27 (18.5%) in G1, 11/26 (42.3%) in G2 and 18/27 (48.1%) in the G3, with at least one episode of infection (p<0.05).

CONCLUSION: These data suggest that daily consumption of concentrated cranberry juice can significantly prevent the recurrence of symptomatic UTIs in children.

Study Type : Human Study

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