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Depression: 21st Century Solutions + The Dark Side of Wheat

Abstract Title:

Creatine monohydrate in muscular dystrophies: A double-blind, placebo-controlled clinical study.

Abstract Source:

Neurology. 2000 May 9;54(9):1848-50. PMID: 10802796

Abstract Author(s):

M C Walter, H Lochmüller, P Reilich, T Klopstock, R Huber, M Hartard, M Hennig, D Pongratz, W Müller-Felber

Abstract:

The authors assessed the safety and efficacy of creatine monohydrate (Cr) in various types of muscular dystrophies in a double-blind, crossover trial. Thirty-six patients (12 patients with facioscapulohumeral dystrophy, 10 patients with Becker dystrophy, 8 patients with Duchenne dystrophy, and 6 patients with sarcoglycan-deficient limb girdle muscular dystrophy) were randomized to receive Cr or placebo for 8 weeks. There was mild but significant improvement in muscle strength and daily-life activities by Medical Research Council scales and the Neuromuscular Symptom Score. Cr was well tolerated throughout the study period.

Study Type : Human Study

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Depression: 21st Century Solutions + The Dark Side of Wheat

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