Drug-induced acute autoimmune hepatitis during combination therapy with atorvastatin and ezetimibe has been reported. - GreenMedInfo Summary

Abstract Title:

Drug-induced acute autoimmune hepatitis during combination therapy with atorvastatin and ezetimibe.

Abstract Source:

Ann Clin Biochem. 2005 Sep ;42(Pt 5):402-4. PMID: 16168199

Abstract Author(s):

Charles van Heyningen

Article Affiliation:

Clinical Laboratories, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, UK. charles.vanheyningen@aht.nwest.nhs.uk

Abstract:

A case is presented of a patient who developed acute hepatitis during cholesterol-lowering treatment with atorvastatin and ezetimibe. Further investigations reveal a probable drug-induced autoimmune hepatitis, and ezetimibe is considered to be the most likely causal agent. This case is the first report of an autoimmune hepatitis associated with ezetimibe therapy.

Article Published Date : Sep 01, 2005
Study Type : Human: Case Report
Additional Links
Diseases : Drug-Induced Toxicity : CK(560) : AC(78), Hepatitis : CK(64) : AC(23), Statin-Induced Pathologies : CK(1570) : AC(315)
Pharmacological Actions : Anticholesteremic Agents : CK(669) : AC(142)
Additional Keywords : Drug Interaction : CK(64) : AC(8)
Problem Substances : Atorvastatin : CK(491) : AC(90)

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