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Depression: 21st Century Solutions + The Dark Side of Wheat

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Abstract Title:

Evaluation of antioxidant and anti-inflammatory activity of green coffee beans methanolic extract in rat skin.

Abstract Source:

Nat Prod Res. 2018 Dec 3:1-7. Epub 2018 Dec 3. PMID: 30507264

Abstract Author(s):

Simona Pergolizzi, Valeria D'Angelo, Marialuisa Aragona, Paola Dugo, Francesco Cacciola, Gioele Capillo, Giacomo Dugo, Eugenia Rita Lauriano

Article Affiliation:

Simona Pergolizzi

Abstract:

Since a long time caffeine has been used in pharmaceutical and cosmetic preparations due to its favorable effects on the skin. The aim of this study was to evaluate the topical anti-inflammatory activity (carrageenan-induced paw oedema) of an ointment prepared using a methanolic extract from green beans of C. robusta via histology. Results showed that the treatment with the ointment reduced the paw oedema within 3 and 5 h post-carrageenan administration. The immunohistochemical evaluations of αSMA, Langerin and S100 gave further support to the morphological analysis. Finally, the methanolic extract from green beans of C. robusta proved to possess elevated free radical scavenger capability by DPPH assay, which may contribute to the observed anti-inflammatory activity.

Study Type : Animal Study

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Sayer Ji
Founder of GreenMedInfo.com

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Depression: 21st Century Solutions + The Dark Side of Wheat

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