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Depression: 21st Century Solutions + The Dark Side of Wheat

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Abstract Title:

Flavonoid glycosides and alkaloids from the embryos of Nelumbo nucifera seeds and their antioxidant activity.

Abstract Source:

Fitoterapia. 2018 Jan 22. Epub 2018 Jan 22. PMID: 29371159

Abstract Author(s):

Xi-Lan Jiang, Lun Wang, En-Jun Wang, Guo-Lin Zhang, Bin Chen, Ming-Kui Wang, Fu Li

Article Affiliation:

Xi-Lan Jiang

Abstract:

Chemical investigation of the embryos of Nelumbo nucifera afforded four new flavone C-glycosides, named nelumbosides A-D (1-4), together with nine known ones, comprising five flavonoids (5-9) and four alkaloids (10-13). The chemical structures of the new compounds were elucidated by 1D, 2D-NMR and HR-ESI-MS techniques, together with chemical methods. Nelumbosides A-D (1-4) are rarely present in naturally occurring flavone C-glycosides featuring a 4-hydroxystyrene unit connected to the flavonoid skeleton. Compounds 2-13 were evaluated for their antioxidant activity by ABTS and DPPH radical-scavenging assay. Among them, compounds 2, 6, 7 and 11 exhibited strong scavenging activity with SC50 values ranging from 12.07 to 25.68μM compared with the positive control l-ascorbic acid.

Study Type : In Vitro Study

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Sayer Ji
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Depression: 21st Century Solutions + The Dark Side of Wheat

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