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Depression: 21st Century Solutions + The Dark Side of Wheat

Article Publish Status: FREE
Abstract Title:

Clinical evaluation of a formulation containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritis.

Abstract Source:

Mol Med Rep. 2013 Nov ;8(5):1542-8. Epub 2013 Aug 29. PMID: 24002213

Abstract Author(s):

Reji Kizhakkedath

Article Affiliation:

Reji Kizhakkedath

Abstract:

A formulation containing Curcuma longa and Boswellia serrata extracts (CB formulation) was evaluated for safety and efficacy in osteoarthritic patients and directly compared with the selective COX-2 inhibitor, celecoxib. In total, 54 subjects were screened, 30 subjects were enrolled and 28 completed the study. The treatment was well tolerated and did not produce any adverse effect in patients, as judged by the vital signs, hemogram, liver and renal function tests. The CB formulation at 500 mg administered twice a day, was more successful than administering celecoxib 100 mg twice a day for symptom scoring and clinical examination. The formulation was found to be safe and no dose-related toxicity was found.

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Sayer Ji
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Depression: 21st Century Solutions + The Dark Side of Wheat

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