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Depression: 21st Century Solutions + The Dark Side of Wheat

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Article Publish Status: FREE
Abstract Title:

Assessment of Total Antioxidant Capacity and Antimicrobial Activity of Glycyrrhiza glabra in Saliva of HIV-Infected Patients.

Abstract Source:

J Pharm Bioallied Sci. 2017 Nov ;9(Suppl 1):S237-S240. PMID: 29284971

Abstract Author(s):

Eby Aluckal, Asif Ismail, Anoopa Paulose, Sanju Lakshmanan, M S Balakrishnan, Benoy Mathew, Vikneshan M, Abraham Kunnilathu

Article Affiliation:

Eby Aluckal

Abstract:

Objectives: The objectives of this study were to evaluate the antimicrobial activity and total antioxidant capacity (TAC) of licorice in Saliva of HIV/AIDS patients.

Materials and Methods: Saliva specimens were collected from 20 people living with HIV infection, with CD4 count<500 cells/mm3 from people infected with HIV/AIDS in Mangalore city, India. A combination of amoxicillin-clavulanic acid and nystatin was taken as the positive control and normal saline as negative control. Results were compared using one-way analysis of variance followed by Tukey's post hoc analysis in SPSS 19.

Results: The TAC was evaluated spectrophotometrically at 695nm using the phosphomolybdenum method. Glycyrrhiza glabra showed a statistically significant reduction (P<0.05) in total Candida count. The TAC of G. glabra was found to be 4.467 mM/L.

Conclusions: G. glabra extracts showed good anticandidal activity and also high antioxidant property which reduces the oxidative stress of HIV-infected people.

Study Type : Human Study

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Depression: 21st Century Solutions + The Dark Side of Wheat

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