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Depression: 21st Century Solutions + The Dark Side of Wheat

Abstract Title:

Gluten intolerance and skin diseases.

Abstract Source:

Eur J Dermatol. 2006 Jan-Feb;16(1):4-11. PMID: 16436335

Abstract Author(s):

Philippe Humbert, Fabien Pelletier, Brigitte Dreno, Eve Puzenat, François Aubin

Article Affiliation:

Department of Dermatology, University of Franche-Comté, CHU Saint Jacques, 25030 Besançon, France. philippe.humbert@univ-fcomte.fr

Abstract:

Gluten sensitivity with or without coeliac disease (CD) symptoms and intestinal pathology has been suggested as a potentially treatable cause of various diseases. CD is a chronic disease which improves on withdrawal of wheat gliadins and barley, rye and oat prolamins from the diet. There have been numerous reports linking CD with several skin conditions. A body of evidence shows that dermatitis herpetiformis is actually a cutaneous manifestation of CD. Autoimmune diseases, allergic diseases, psoriasis and miscellaneous diseases have also been described with gluten intolerance. Dermatologists should be familiar with the appraisal of gluten sensitive enteropathy and should be able to search for an underlying gluten intolerance (GI). Serological screening by means of antigliadin, antiendomysial and transglutaminase antibodies should be performed. HLA typing is often useful in association with serologic tests. Intestinal biopsy is usually needed to establish the diagnosis of CD or GI. Thus, gluten intolerance gives rise to a variety of dermatological manifestations which may benefit from a gluten-free diet.

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Sayer Ji
Founder of GreenMedInfo.com

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Depression: 21st Century Solutions + The Dark Side of Wheat

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