Abstract Title:

Sugar-sweetened beverages, serum uric acid, and blood pressure in adolescents.

Abstract Source:

J Pediatr. 2009 Jun;154(6):807-13. Epub 2009 Apr 17. PMID: 19375714

Abstract Author(s):

Stephanie Nguyen, Hyon K Choi, Robert H Lustig, Chi-yuan Hsu

Article Affiliation:

Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA. nguyens@peds.ucsf.edu

Abstract:

OBJECTIVE: To evaluate whether sugar-sweetened beverage consumption, a significant source of dietary fructose, is associated with higher serum uric acid levels and blood pressure in adolescents. STUDY DESIGN: We analyzed cross-sectional data from 4867 adolescents aged 12 to 18 years in the National Health and Nutrition Examination Survey, 1999-2004. Dietary data were assessed from 24-hour dietary recall interviews. Sugar-sweetened beverages included fruit drinks, sports drinks, soda, and sweetened coffee or tea. We used multivariate linear regression to evaluate the association of sugar-sweetened beverage consumption with serum uric acid and with blood pressure. RESULTS: Adolescents who drank more sugar-sweetened beverages tended to be older and male. In the adjusted model, serum uric acid increased by 0.18 mg/dL and systolic blood pressure z-score increased by 0.17 from the lowest to the highest category of sugar-sweetened beverage consumption (P for trend, .01 and .03, respectively). CONCLUSIONS: These results from a nationally representative sample of US adolescents indicate that higher sugar-sweetened beverage consumption is associated with higher serum uric acid levels and systolic blood pressure, which may lead to downstream adverse health outcomes.

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