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Abstract Title:

Protective Effect of Morocco Carob Honey Against Lead-Induced Anemia and Hepato-Renal Toxicity.

Abstract Source:

Cell Physiol Biochem. 2016 ;39(1):115-22. Epub 2016 Jun 20. PMID: 27322825

Abstract Author(s):

Aicha Fassi Fihri, Noori S Al-Waili, Redouan El-Haskoury, Meryem Bakour, Afaf Amarti, Mohammad J Ansari, Badiaa Lyoussi

Article Affiliation:

Aicha Fassi Fihri

Abstract:

BACKGROUND/AIMS: Natural honey has many biological activities including protective effect against toxic materials. The aim of this study was to evaluate the protective effect of carob honey against lead-induced hepato-renal toxicity and lead-induced anemia in rabbits.

METHODS: Twenty four male rabbits were allocated into four groups six rabbits each; group 1: control group, received distilled water (0.1 ml / kg.b.wt /daily); group 2: received oral lead acetate (2 g/kg.b.wt/daily); group 3: treated with oral honey (1g /kg.b.wt/daily) and oral lead (2 g/kg.b.wt/daily), and group 4: received oral honey (1 g/kg.b.wt/daily). Honey and lead were given daily during 24 days of experimentation. Laboratory tests and histopathological evaluations of kidneys were done.

RESULTS: Oral administration of lead induced hepatic and kidney injury and caused anemia during three weeks of the exposure. Treatment with honey prevented hepato-renal lead toxicity and ameliorated lead-induced anemia when honey was given to animals during lead exposure.

CONCLUSION: It might be concluded that honey has a protective effect against lead-induced blood, hepatic and renal toxic effects.

Study Type : Animal Study

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