Article Publish Status: FREE
Abstract Title:

Increased risk of noninfluenza respiratory virus infections associated with receipt of inactivated influenza vaccine.

Abstract Source:

Clin Infect Dis. 2012 Jun ;54(12):1778-83. Epub 2012 Mar 15. PMID: 22423139

Abstract Author(s):

Benjamin J Cowling, Vicky J Fang, Hiroshi Nishiura, Kwok-Hung Chan, Sophia Ng, Dennis K M Ip, Susan S Chiu, Gabriel M Leung, J S Malik Peiris

Article Affiliation:

Benjamin J Cowling

Abstract:

We randomized 115 children to trivalent inactivated influenza vaccine (TIV) or placebo. Over the following 9 months, TIV recipients had an increased risk of virologically-confirmed non-influenza infections (relative risk: 4.40; 95% confidence interval: 1.31-14.8). Being protected against influenza, TIV recipients may lack temporary non-specific immunity that protected against other respiratory viruses.

Study Type : Human Study
Additional Links
Adverse Pharmacological Actions : Immunotoxic : CK(484) : AC(118)

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