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Abstract Title:

Postvaccination miller fisher syndrome.

Abstract Source:

Arch Neurol. 2011 Oct ;68(10):1327-9. PMID: 21987549

Abstract Author(s):

Ashkan Shoamanesh, Kristine Chapman, Anthony Traboulsee

Article Affiliation:

Department of Medicine and Neurology, University of British Columbia, 1103-1068 W Broadway Ave, Vancouver, BC V6H 0A7, Canada. ashkan.sho@gmail.com.

Abstract:

BACKGROUND: Although postvaccination Guillain-Barré syndrome is commonly reported, there have only been 2 previously reported cases of postvaccination Miller Fisher syndrome, and none in association with the novel influenza A(H1N1) vaccine.

OBJECTIVE: To describe a case of Miller Fisher syndrome following receipt of the seasonal influenza and novel influenza A(H1N1) vaccine.

DESIGN: Case report and literature review.

SETTING: Vancouver General Hospital. Patient  A 77-year-old Chinese woman.

RESULTS: The patient presented with ophthalmoplegia, ataxia, areflexia, and a sensory neuropathy within 2 weeks of immunization. Findings of parainfectious evaluation were unremarkable. Treatment with 2 courses of intravenous immunoglobulin led to clinical improvement. Her presentation and natural history of disease were similar to the 2 previously published cases.

CONCLUSIONS: We present the third case of postvaccination Miller Fisher syndrome in the literature and the first associated with the novel influenza A(H1N1) vaccine.

Study Type : Human: Case Report

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Sayer Ji
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