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Abstract Title:

White matter lesions suggestive of amyotrophic lateral sclerosis attributed to celiac disease.

Abstract Source:

BJU Int. 2007 Mar;99(3):619-22. Epub 2006 Nov 28. PMID: 19910450

Abstract Author(s):

K J Brown, V Jewells, H Herfarth, M Castillo

Abstract:

SUMMARY: CD is an autoimmune-mediated disorder of the gastrointestinal tract. Initial symptom presentation is variable and can include neurologic manifestations that may comprise ataxia, neuropathy, dizziness, epilepsy, and cortical calcifications rather than gastrointestinal-hindering diagnosis and management. We present a case of a young man with progressive neurologic symptoms and brain MR imaging findings worrisome for ALS. During the diagnostic work-up, endomysium antibodies were discovered, and CD was confirmed by upper gastrointestinal endoscopy with duodenal biopsies. MR imaging findings suggestive of ALS improved after gluten-free diet institution.

 

Study Type : Human Study

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Sayer Ji
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