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Abstract Title:

Bio-antimutagenic effect of L-cysteine on diiodohydroxyquinoline-induced micronuclei in Swiss mice.

Abstract Source:

Mutat Res. 1987 Apr;187(4):219-22. PMID: 3104778

Abstract Author(s):

S Ghaskadbi, S V Pavaskar, V G Vaidya

Abstract:

The mutagenic potential of diiodohydroxyquinoline (DIHQ), a common anti-amebic drug, was tested using the in vivo micronucleus test in Swiss mice following oral administration. It was found to be mutagenic in a dose-dependent manner. Using the same model system, the bio-antimutagenic effect of the sulfhydryl compound L-cysteine against DIHQ was established.


Study Type : Animal Study

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