Abstract Title:

[Adrenal cortex functional activity in pantothenate deficiency and the administration of the vitamin or its derivatives].

Abstract Source:

Vopr Pitan. 1985 Jul-Aug;(4):51-4. PMID: 4060684

Abstract Author(s):

Iu A Tarasov, V M Sheĭbak, A G Moĭseenok

Abstract:

Study of the corticosteroid content in the adrenals and blood of rats under pantothenate deficiency has demonstrated a decrease in adrenocortical function. A single administration of pantothenate in a dose of 3.3 mg/kg reduced the influence of hypovitaminosis on the adrenals. The pantothenate derivatives (pantethine, 4'-phosphopantothenate and CoA in particular) injected to intact animals in a single dose equimolar to 3.3 mg/kg calcium pantothenate per kg bw had a marked steroidogenous effect.

Study Type : Animal Study

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