This patient, who previously had recurrent seizures despite treatment with antiepileptic drugs, became seizure-free after normalization of vitamin B6 levels. - GreenMedInfo Summary
Seizures Related to Vitamin B6 Deficiency in Adults.
J Epilepsy Res. 2015 Jun ;5(1):23-4. Epub 2015 Jun 30. PMID: 26157671
Dong-Gun Lee
Vitamin B6 is closely associated with functions of the nervous, immune, and endocrine systems. Its deficiency may result in neurological disorders including convulsions and epileptic encephalopathy. Until today, this has only been reported in infants, children, and critically ill adult patients. We report a case of a 36year-old man with chronic alcoholism who presented with seizures after gastrointestinal disturbance. His seizures persisted even after treatment with antiepileptic drugs, but eventually disappeared after administration of pyridoxine. Hence, vitamin B6 deficiency may cause seizures in adult patients with chronic alcoholism.