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Abstract Title:

A geographical analysis of breast cancer clustering in southern Ontario: generating hypotheses on environmental influences.

Abstract Source:

Int J Environ Health Res. 2011 Nov 30. Epub 2011 Nov 30. PMID: 22129067

Abstract Author(s):

Isaac N Luginaah, Kevin M Gorey, Tor H Oiamo, Kathy X Tang, Eric J Holowaty, Caroline Hamm, Frances C Wright

Article Affiliation:

a Department of Geography , The University of Western Ontario , London , ON , Canada , N6A 3K7.

Abstract:

This article presents the results of spatial analysis of breast cancer clustering in southern Ontario. Data from the Cancer Care Ontario were analyzed using the Scan Statistic at the level of county, with further analysis conducted within counties that were identified as primary clusters at the dissemination area level. The results identified five counties as primary clusters of women diagnosed with breast cancer between 1986 and 2002: Essex (relative risk [RR] = 1.096-1.061; p < 0.001), Lambton (RR = 1.05-1.167), Chatham-Kent (RR = 1.133-1.191), Niagara (RR = 1.228-1.290) and Toronto (RR = 1.152-1.146). The within county analysis revealed several DAs with significantly higher (RR > 3, p < 0.05) rates of breast cancer, and supports our hypothesis that breast cancer risk in southern Ontario may be associated with industrial and environmental (such as pesticides) pollutants. Further research is needed to verify the environmental links within the identified clusters.

Study Type : Human Study

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Sayer Ji
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