Phyllanthus urinaria extract may have a therapeutic role to play in the treatment of hepatoma. - GreenMedInfo Summary

Abstract Title:

[Effects of extracts from Phyllanthus urinaria L. on HBsAg production in PLC/PRF/5 cell line].

Abstract Source:

Zhongguo Zhong Yao Za Zhi. 1993 Aug;18(8):496-8, 511 PMID: 8011099

Abstract Author(s):

X H Ji, Y Z Qin, W Y Wang, J Y Zhu, X T Liu

Abstract:

Experiment on the effect of extracts from Phyllanthus urinaria on HBsAg production in PLC/PRF/5 human hepatoma cell line showed that the production was decreased markedly 48 hours after the treatment of cells with 2-4 mg/ml Phyllanthus urinaria, especially in combination with 10(-5) mol/L of Ara-A. The decrease of extracellular HB-sAg excretion seems to stem from the inhibition of intracellular HBsAg formation.

 

Article Published Date : Aug 01, 1993
Study Type : In Vitro Study
Additional Links
Substances : Phyllanthus urinaria : CK(57) : AC(35)
Diseases : Hepatoma : CK(37) : AC(32)

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Key Research Topics

Disease

Hepatoma

Substance

Phyllanthus urinaria

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