n/a
Article Publish Status: FREE
Abstract Title:

Beet Stalks and Leaves (L.) Protect Against High-Fat Diet-Induced Oxidative Damage in the Liver in Mice.

Abstract Source:

Nutrients. 2018 Jul 5 ;10(7). Epub 2018 Jul 5. PMID: 29976910

Abstract Author(s):

Isabela M Lorizola, Cibele P B Furlan, Mariana Portovedo, Marciane Milanski, Patrícia B Botelho, Rosângela M N Bezerra, Beatriz R Sumere, Maurício A Rostagno, Caroline D Capitani

Article Affiliation:

Isabela M Lorizola

Abstract:

Some flavonoids identified in beet stalks can help the antioxidant endogenous defenses during a chronic inflammation process. The current study investigates the effect of polyphenols present in beet stalks and leaves on liver oxidative damage in mice fed a high-fat diet (HF). The control (CT) or HF diet groups were supplemented with dehydrated beet stalks and leaves (SL) or beet stalk and leaf ethanolic extract (EX). In terms of Vitexin-rhaminoside equivalents (VRE), EX groups received ~5.91 mg of VRE·100 gdiet, while the SL groups received ~3.07 mg VRE·100 gdiet. After 8 weeks, we evaluated fasting blood glucose; cholesterol, hepatic Malondialdehyde (MDA) levels and hepatic Glutathione (GSH), Glutathione peroxidase (GPx), Glutathione reductase (GR) and Superoxide dismutase (SOD) activity. Dehydrated beet stalks and leaves (HFSL) attenuated the deleterious effects of a HF diet on lipid metabolism, reduced fasting blood glucose levels, ameliorated cholesterol levels and reduced GPx and GR activities (<0.05) compared to the HF group. However; the addition of ethanolic extract from beet stalks and leaves was unable (>0.05) to prevent the liver damage caused by HF diet in mice. The presence of flavonoids, such as Vitexin derivatives in beet stalks and leaves can help the liver damage induced by HF diet.

Print Options


Key Research Topics

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2024 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.