Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get two FREE E-Books

Our newsletter serves 250,000 with essential news, research & healthy tips, daily.

Depression: 21st Century Solutions + The Dark Side of Wheat

Abstract Title:

[The Immunomodulatory and Anti-allergy Effects of Lactobacilli].

Abstract Source:

Sichuan Da Xue Xue Bao Yi Xue Ban. 2016 Mar ;47(2):192-6. PMID: 27263293

Abstract Author(s):

Xi Shen, Ming Li, Lei Shi, Nan Ling, Miao He, Shu-yue Wang, Fang He

Article Affiliation:

Xi Shen

Abstract:

OBJECTIVE: This study was conducted to evaluate the potent immunomodulatory effects of Lactobacilli and their possible anti-allergic effects.

METHODS: Lactobacillus plantarum LP45 (LP45), Lactobacillus acidophilus La28 (La28), Lactobacillus acidophilus 6091 (6091), Lactobacillus rhamnosus GG (LGG) were orally administrated to male BALB/C mice, respectively for 28 d. The immune organ index, serum Th1 cytokines [interferon-γ (IFN-γ), interleukin-12 (IL-12)] and Th2 cytokines IL-6 of the tested mice were analyzed with ELISA after intervention. Furthermore, La28, 6901 were also orally fed to ovalbumin (OVA)-sensitized male BALB/C. The serum total IgE of the tested mice was analyzed with ELISA after intervention.

RESULTS: No statistical difference was found in immune organ index among the tested four strains. La28 significantly decreased serum IL-6 of the tested mice after 14 d and 28 d compared to those in control (P<0.05). After 28 d, 6091 also significantly reduced serum IL-6 of the tested mice (P<0.05). La28 significantly suppressed the increase of serum total IgE of the tested mice (P<0.05).

CONCLUSION: The present study indicates that the immunomodulatory effects of Lactobacilli might be strain-dependent. Among the tested strains of Lactobacilli, La28 and 6091 may have possibility to influence the Th2 immunity of host animal. La28 may also posse potent ability to alter IgE mediated allergy by the way to affect Th1/Th2 balance of host animal.

Print Options


Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get two FREE E-Books

Our newsletter serves 250,000 with essential news, research & healthy tips, daily.

Depression: 21st Century Solutions + The Dark Side of Wheat

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2018 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.