Abstract Title:

Effect of gluten-free diet on pregnancy outcome in celiac disease patients with recurrent miscarriages.

Abstract Source:

Dig Dis Sci. 2008 Nov;53(11):2925-8. Epub 2008 Mar 27. PMID: 18368491

Abstract Author(s):

Antonio Tursi, Gianmarco Giorgetti, Giovanni Brandimarte, Walter Elisei

Article Affiliation:

Lorenzo Bonomo Hospital, Via Torino, 49, 70031, Andria, BA, Italy. [email protected]

Abstract:

PURPOSE: Available literature data show that celiac disease (CD) is a frequent cause of recurrent miscarriage. However, data are lacking for pregnancy outcome when the patient is on a gluten-free diet (GFD). A case-control study about the effect of GFD on pregnancy was conducted from 1995 to 2006. A cohort of 13 women (mean age 32 years, range 22-38 years) affected by CD with recurrent miscarriages was observed. In all of them several causes of miscarriage (gynecological, endocrine, hematological, etc.) were excluded. All patients were started on a gluten-free diet and were reassessed throughout a long-term follow-up period to evaluate the outcome of pregnancy.

RESULTS: Six of 13 became pregnant (46.15%) as follows: 1 patient (7.69%) 1 year after GFD was started, 3 patients (23.07%) 2 years after GFD was started, 1 patient (7.69%) after 3 years, and finally 1 (7.69%) 4 years after GFD was started. Moreover, two patients (16.66%) had multiple pregnancies (one had had two childbirths and another had undergone three births within a 7-year follow-up period under GFD).

CONCLUSIONS: GFD seems to favor a positive outcome of pregnancy in most CD patients with recurrent miscarriage.

Study Type : Meta Analysis

Print Options


Key Research Topics

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2024 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.