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Abstract Title:

Red meat and processed meat intake and risk of cutaneous melanoma in white women and men: Two prospective cohort studies.

Abstract Source:

J Am Acad Dermatol. 2018 Apr 23. Epub 2018 Apr 23. PMID: 29698709

Abstract Author(s):

Hsi Yen, Wen-Qing Li, Ashar Dhana, Tricia Li, Abrar Qureshi, Eunyoung Cho

Article Affiliation:

Hsi Yen

Abstract:

BACKGROUND: Red and processed meat consumption has been associated with increased risk of several cancers, but association with cutaneous melanoma risk has been inconclusive.

OBJECTIVE: To investigate the association between red and processed meat intake and melanoma risk.

METHODS: Dietary information was assessed using food frequency questionnaires in two prospective cohorts - 75,263 women from the Nurses' Health Study (1984 - 2010) and 48,523 men from the Health Professionals Follow-up Study (1986 - 2010). Melanoma cases were confirmed by review of pathological records. Pooled multivariable hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox proportional hazards models.

RESULTS: A total of 679 female and 639 male melanoma cases were documented during follow-up. Red and processed meat intake was inversely associated with melanoma risk (P for trend = 0.002); the pooled HRs (95% CIs) of the two cohorts were 1.00 (reference), 1.00 (0.87 - 1.14), 0.98 (0.86 - 1.13), 0.89 (0.77 - 1.02), and 0.81 (0.70 - 0.95) for increasing quintiles of intake.

LIMITATIONS: Findings may have limited generalizability, as the cohorts were limited to white health professionals.

CONCLUSION: Red and processed meat intake was inversely associated with melanoma risk in these two cohorts.

Study Type : Human Study
Additional Links
Additional Keywords : Risk Factors : CK(3057) : AC(392)
Problem Substances : Meat : CK(129) : AC(14)

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Sayer Ji
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