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Abstract Title:

Bacterial Nanocellulose Loaded with Bromelain: Assessment of Antimicrobial, Antioxidant and Physical-Chemical Properties.

Abstract Source:

Sci Rep. 2017 Dec 21 ;7(1):18031. Epub 2017 Dec 21. PMID: 29269741

Abstract Author(s):

Janaína Artem Ataide, Nathália Mendes de Carvalho, Márcia de Araújo Rebelo, Marco Vinícius Chaud, Denise Grotto, Marli Gerenutti, Mahendra Rai, Priscila Gava Mazzola, Angela Faustino Jozala

Article Affiliation:

Janaína Artem Ataide

Abstract:

Bacterial nanocellulose (BNC) has desirable properties for wound healing such as high purity, good shape retention, and high water binding capacity. Bromelain is a protease found in pineapple tissues and has been applied in several fields, it has anti-inflammatory and anticancer properties, promotes cell apoptosis, amongst others. In this work, a BNC based device for the controlled release of bromelain was developed. BNC were submersed in sterilized bromelain solution and incubated at 25 °C under 100 rpm for 24 h. Physical-chemical properties, protein concentration, antioxidant and antimicrobial activities were measured. Results demonstrate that BNC could improve bromelain antimicrobial activity 9 times. Those findings allow concluding that bromelain is a promising moleculeto be incorporated into BNC's. The BNC's characteristics seem to represent a new promising delivery system of the loaded biomolecule, and protected from external actions.

Study Type : In Vitro Study

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Sayer Ji
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