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Depression: 21st Century Solutions + The Dark Side of Wheat

Abstract Title:

Antihypertensive effects and mechanisms of chlorogenic acids.

Abstract Source:

Hypertens Res. 2012 Apr ;35(4):370-4. Epub 2011 Nov 10. PMID: 22072103

Abstract Author(s):

Youyou Zhao, Junkuan Wang, Olivier Ballevre, Hongliang Luo, Weiguo Zhang

Article Affiliation:

Nestle Research Center Beijing, No. 5 DiJin Road, Beijing, China.

Abstract:

Chlorogenic acids (CGAs) are potent antioxidants found in certain foods and drinks, most notably in coffee. In recent years, basic and clinical investigations have implied that the consumption of chlorogenic acid can have an anti-hypertension effect. Mechanistically, the metabolites of CGAs attenuate oxidative stress (reactive oxygen species), which leads to the benefit of blood-pressure reduction through improved endothelial function and nitric oxide bioavailability in the arterial vasculature. This review article highlights the physiological and biochemical findings on this subject and highlights some remaining issues that merit further scientific and clinical exploration. In the framework of lifestyle modification for the management of cardiovascular risk factors, the dietary consumption of CGAs may hold promise for providing a non-pharmacological approach for the prevention and treatment of high blood pressure.

Study Type : Review

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Sayer Ji
Founder of GreenMedInfo.com

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Depression: 21st Century Solutions + The Dark Side of Wheat

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