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Article Publish Status: FREE
Abstract Title:

Prenatal Exposure to BPA and Offspring Outcomes: The Diabesogenic Behavior of BPA.

Abstract Source:

Dose Response. 2015 Apr-Jun;13(2):1559325815590395. Epub 2015 Jun 12. PMID: 26676280

Abstract Author(s):

Paloma Alonso-Magdalena, Iván Quesada, Ángel Nadal

Article Affiliation:

Paloma Alonso-Magdalena

Abstract:

Obesity and type 2 diabetes mellitus (T2DM) are the most common metabolic disorders, with prevalence rates that are reaching epidemic proportions. Both are complex conditions affecting virtually all ages and with serious health consequences. The underlying cause of the problem is still puzzling, but both genetic and environmental factors including unhealthy diet, sedentary lifestyle, or the exposure to some environmental endocrine disrupting chemicals (EDCs) are thought to have a causal influence. In addition, the impact of early environment has recently emerged as an important factor responsible for the increased propensity to develop adult-onset metabolic disease. Suboptimal maternal nutrition during critical windows in fetal development is the most commonly studied factor affecting early programming of obesity and T2DM. In recent years, increasing experimental evidence shows that exposure to EDCs could also account for this phenomenon. In the present review, we will overview the most relevant findings that confirm the critical role of bisphenol-A, one of the most widespread EDCs, in the development of metabolic disorders.

Study Type : Review

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Sayer Ji
Founder of GreenMedInfo.com

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