Simvastatin-induced lupus-like syndrome has been reported. - GreenMedInfo Summary
Abstract Title:
Simvastatin-induced lupus-like syndrome.
Abstract Source:
Tenn Med. 2000 Jan ;93(1):21-2. PMID: 10628262
Article Affiliation:
Department of Internal Medicine, James H. Quillen College of Medicine, East Tennessee State University, Johnson City 37614-0622, USA.
Abstract:
The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors are widely used as cholesterol lowering agents that have an acceptable safety profile. As a group, this class of drugs has been associated with few immunologic reactions. Simvastatin (Zocor) has been linked to three cases of drug-induced lupus-like syndrome. We report the case of an additional patient who developed pleurisy and arthralgia after he started taking this low-density lipoprotein and cholesterol-lowering agent.
Article Published Date : Jan 01, 2000
Study Type : Human: Case Report
Additional Links
Diseases : Arthralgia : CK(24) : AC(4), Lupus-Like Syndrome : CK(44) : AC(8), Pleurisy : CK(39) : AC(16), Statin-Induced Pathologies : CK(1848) : AC(369)
Pharmacological Actions : Anticholesteremic Agents : CK(3078) : AC(646)
Problem Substances : Simvastatin : CK(791) : AC(165)
