Simvastatin-induced mononeuropathy has been reported. - GreenMedInfo Summary

Abstract Title:

Simvastatin-induced mononeuropathy multiplex: case report.

Abstract Source:

Arq Neuropsiquiatr. 2004 Jun ;62(2B):540-2. Epub 2004 Jul 20. PMID: 15273860

Abstract Author(s):

Rosana H Scola, Ana P Trentin, Francisco M B Germiniani, Elcio J Piovesan, Lineu C Werneck

Article Affiliation:

Department of Medicine, Universidade Federal do Paraná, Curitiba PR, Brazil. scola@hc.ufpr.br

Abstract:

The association between the use of statins and neuromuscular disease is currently being intensely discussed. We relate a 63 years old man with possible case of statin-induced neuropathy in a patient with dislipidemia in use of simvastatina at high doses. The electrophysiologic studies disclosed findings compatible with mononeuropathy multiplex, suggested by clinical prescutation of asymmetrical numbness and weakness. More common causes of mononeuropathy multiplex were excluded and the patient improved after the discontinuation of the drug.

Pubmed Data : Arq Neuropsiquiatr. 2004 Jun ;62(2B):540-2. Epub 2004 Jul 20. PMID: 15273860
Article Published Date : Jun 01, 2004
Study Type : Human: Case Report
Additional Links
Diseases : Neuropathies : CK(450) : AC(67), Statin-Induced Pathologies : CK(1543) : AC(315)
Problem Substances : Simvastatin : CK(760) : AC(143), Statin Drugs : CK(3769) : AC(442)
Adverse Pharmacological Actions : Neurotoxic : CK(1042) : AC(170)

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