Ulcerative colitis after statin treatment has been reported. - GreenMedInfo Summary

Abstract Title:

Ulcerative colitis after statin treatment.

Abstract Source:

Postgrad Med J. 2002 May ;78(919):286-7. PMID: 12151572

Abstract Author(s):

W E Rea, D C S Durrant, D A R Boldy

Article Affiliation:

Department of Respiratory Medicine, Pilgrim Hospital, United Lincolnshire Hospitals NHS Trust, Boston, Lincs, UK.

Abstract:

Statin treatment is widely used in both primary and secondary prevention of diseases in which hyperlipidaemia is a major risk factor, for example, ischaemic heart disease. The development of ulcerative colitis as an adverse reaction to simvastatin is reported, which, despite withdrawal of the drug, proved fatal. The adverse reaction profile of the statins is reviewed, which suggests that this is a class effect and not one limited to simvastatin.

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Pubmed Data : Postgrad Med J. 2002 May ;78(919):286-7. PMID: 12151572
Article Published Date : May 01, 2002
Study Type : Human: Case Report
Additional Links
Diseases : Statin-Induced Pathologies : CK(1543) : AC(315), Ulcerative Colitis : CK(461) : AC(40)
Pharmacological Actions : Anticholesteremic Agents : CK(699) : AC(142)
Problem Substances : Simvastatin : CK(760) : AC(143), Statin Drugs : CK(3769) : AC(442)
Adverse Pharmacological Actions : Inflammatory : CK(135) : AC(37)

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