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Abstract Title:

Potential activity of aqueous extract of culinary-medicinal Lion's Mane mushroom, Hericium erinaceus (Bull.: Fr.) Pers. (Aphyllophoromycetideae) in accelerating wound healing in rats.

Abstract Source:

Int J Med Mushrooms. 2011 ;13(1):33-9. PMID: 22135902

Abstract Author(s):

Mahmood Ameen Abdulla, Atieh Abdollahi Fard, Vikineswary Sabaratnam, Kah-Hui Wong, Umah Rani Kuppusamy, Noorlidah Abdullah, Salmah Ismail

Article Affiliation:

Department of Molecular Medicine, Faculty of Medicine, University of Malaya, Kuala, Lumpur, Malaysia. ammeen@um.edu.my

Abstract:

This study was conducted to evaluate the effects of topical application of aqueous extract of Hericium erinaceus fruiting bodies (HEFB) on the rate of wound healing enclosure and histology of the healed wound. Five groups of male Sprague-Dawley rats were experimentally wounded in the posterior neck area. A uniform wound area of 2.00 cm in diameter, using a circular stamp, was excised from the nape of the dorsal neck of all rats with the aid of a round seal. The animal groups were topically treated, respectively, with 0.2 mL each of sterilized distilled water (sdH2O); Intrasite gel; and 20, 30, and 40 mg/mL HEFB. Macroscopically, those rats whose wounds were dressed with HEFB and those in the Intrasite gel-treated group healed earlier than those treated with sdH2O. Histological analysis of healed wounds dressed with HEFB showed less scar width at wound enclosure and the healed wound contained fewer macrophages and more collagen with angiogenesis, compared to wounds dressed with sdH2O. In conclusion, wounds dressed with HEFB significantly enhanced the acceleration of wound healing enclosure in rats.

Study Type : Animal Study

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wound healing with lions mane



Aside from the fact that these animal experiments are horrific I question the above study. It is an evidence based fact that keeping a wound moist will provide the optimal environment for wound healing. If I understand the above study correctly, the one group was treated with water and the other group with Lions Mane and intrasite gel. Rinsing with water will not keep the wound moist as you get a drying effect. Intrasite gel has been proven to adhere to the wound and keeps it moist. That alone will support wound healing. How do we know what the effect of Lions Mane was? Sincerely, Joanne Kersten, Netherlands

wound healing with lions mane



Aside from the fact that these animal experiments are horrific I question the above study. It is an evidence based fact that keeping a wound moist will provide the optimal environment for wound healing. If I understand the above study correctly, the one group was treated with water and the other group with Lions Mane and intrasite gel. Rinsing with water will not keep the wound moist as you get a drying effect. Intrasite gel has been proven to adhere to the wound and keeps it moist. That alone will support wound healing. How do we know what the effect of Lions Mane was? Sincerely, Joanne Kersten, Netherlands
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Sayer Ji
Founder of GreenMedInfo.com

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Easy Turmeric recipes + The Dark Side of Wheat

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